5'-O-(tert-butyl)diphenylsilyl-2'-O-methyl-3'-trifluoromethylsulfonyl-N²-isobutyrylguanosine

Base Information

• Chemical Name: 5'-O-(tert-butyl)diphenylsilyl-2'-O-methyl-3'-trifluoromethylsulfonyl-N²-isobutyrylguanosine
• CAS No.: 1042664-47-0
• Molecular Formula: C₃₂H₃₈F₃N₅O₈SSi
• Molecular Weight: 737.829
• Mol file: 1042664-47-0.mol

Synonyms:5'-O-(tert-butyl)diphenylsilyl-2'-O-methyl-3'-trifluoromethylsulfonyl-N²-isobutyrylguanosine

Chemical Property of 5'-O-(tert-butyl)diphenylsilyl-2'-O-methyl-3'-trifluoromethylsulfonyl-N²-isobutyrylguanosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5'-O-(tert-butyl)diphenylsilyl-2'-O-methyl-3'-trifluoromethylsulfonyl-N²-isobutyrylguanosine

There total 1 articles about 5'-O-(tert-butyl)diphenylsilyl-2'-O-methyl-3'-trifluoromethylsulfonyl-N²-isobutyrylguanosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

trifluoromethane sulfonyl chloride (421-83-0) + 5'-O-(tert-butyl)diphenylsilyl-2'-O-methyl-N2-isobutyrylguanosine (1042664-46-9) → 5'-O-(tert-butyl)diphenylsilyl-2'-O-methyl-3'-trifluoromethylsulfonyl-N2-isobutyrylguanosine (1042664-47-0)

Guidance literature:

With dmap; In acetonitrile; at 0 ℃; for 2h;

DOI:10.1016/j.bmc.2008.03.061

Reference yield: 58.0%

5'-O-(tert-butyl)diphenylsilyl-2'-O-methyl-3'-trifluoromethylsulfonyl-N2-isobutyrylguanosine (1042664-47-0) → C31H38BrN5O5Si (1042664-48-1)

Guidance literature:

With sodium bromide; In acetone; for 3h; Heating;

DOI:10.1016/j.bmc.2008.03.061

upstream raw materials:

trifluoromethane sulfonyl chloride

5'-O-(tert-butyl)diphenylsilyl-2'-O-methyl-N²-isobutyrylguanosine

Downstream raw materials:

C₃₁H₃₈BrN₅O₅Si