artelinic acid

Base Information

• Chemical Name: artelinic acid
• CAS No.: 216963-49-4
• Molecular Formula: C₂₃H₃₀O₇
• Molecular Weight: 418.487
• Mol file: 216963-49-4.mol

Synonyms:artelinic acid

Chemical Property of artelinic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of artelinic acid

There total 5 articles about artelinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

methyl p-<(10-dihydroartemisininoxy)methyl>benzoate (216963-48-3) → artelinic acid (216963-49-4,109637-83-4,120020-26-0)

Guidance literature:

With potassium hydroxide; In methanol; for 48h; Ambient temperature;

DOI:10.1021/jm00394a037

Reference yield:

4-(methoxycarbonyl)benzyl alcohol (6908-41-4,58590-49-1) → artelinic acid (216963-49-4,109637-83-4,120020-26-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / BF₃*Et₂O / diethyl ether / 24 h / Ambient temperature

2: 55 percent / 2.5percent KOH / methanol / 48 h / Ambient temperature

With potassium hydroxide; boron trifluoride diethyl etherate; In methanol; diethyl ether;

DOI:10.1021/jm00394a037

Reference yield:

dihydroartemisinin (71939-50-9) → artelinic acid (216963-49-4,109637-83-4,120020-26-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / BF₃*Et₂O / diethyl ether / 24 h / Ambient temperature

2: 55 percent / 2.5percent KOH / methanol / 48 h / Ambient temperature

With potassium hydroxide; boron trifluoride diethyl etherate; In methanol; diethyl ether;

DOI:10.1021/jm00394a037

upstream raw materials:

methyl p-<(10-dihydroartemisininoxy)methyl>benzoate

4-(methoxycarbonyl)benzyl alcohol

dihydroartemisinin

C₁₂H₁₃O₂(CH₃)3(O)(OO)