(S)-2-aminopropanoic acid [4-(2,3,5,6-tetrafluoropyridin-4-ylethynyl)phenyl]amide hydrochloride

Base Information

Chemical Name:(S)-2-aminopropanoic acid [4-(2,3,5,6-tetrafluoropyridin-4-ylethynyl)phenyl]amide hydrochloride
CAS No.:1185249-08-4
Molecular Formula:C₁₆H₁₁F₄N₃O*ClH
Molecular Weight:373.737
Hs Code.:

Synonyms:(S)-2-aminopropanoic acid [4-(2,3,5,6-tetrafluoropyridin-4-ylethynyl)phenyl]amide hydrochloride

Suppliers and Price of (S)-2-aminopropanoic acid [4-(2,3,5,6-tetrafluoropyridin-4-ylethynyl)phenyl]amide hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-aminopropanoic acid [4-(2,3,5,6-tetrafluoropyridin-4-ylethynyl)phenyl]amide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-aminopropanoic acid [4-(2,3,5,6-tetrafluoropyridin-4-ylethynyl)phenyl]amide hydrochloride

There total 5 articles about (S)-2-aminopropanoic acid [4-(2,3,5,6-tetrafluoropyridin-4-ylethynyl)phenyl]amide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 1208242-22-1
C₂₁H₁₉F₄N₃O₃

: 1185249-08-4
(S)-2-aminopropanoic acid [4-(2,3,5,6-tetrafluoropyridin-4-ylethynyl)phenyl]amide hydrochloride

Guidance literature:: With hydrogenchloride; In tetrahydrofuran;
DOI:10.1021/ja902140m

Reference yield:

: 1185249-11-9
4-(2,3,5,6-tetrafluoropyridin-4-ylethynyl)nitrobenzene

: 1185249-08-4
(S)-2-aminopropanoic acid [4-(2,3,5,6-tetrafluoropyridin-4-ylethynyl)phenyl]amide hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride; tin(ll) chloride / tetrahydrofuran; water / 3.5 h / 20 °C

2: pyridine; trichlorophosphate / 11 h / -20 - 20 °C

3: hydrogenchloride / tetrahydrofuran

With pyridine; hydrogenchloride; tin(ll) chloride; trichlorophosphate; In tetrahydrofuran; water;
DOI:10.1021/ja902140m

Reference yield:

: 1185249-12-0
4-(2,3,5,6-tetrafluoropyridin-4-ylethynyl)aniline

: 1185249-08-4
(S)-2-aminopropanoic acid [4-(2,3,5,6-tetrafluoropyridin-4-ylethynyl)phenyl]amide hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; trichlorophosphate / 11 h / -20 - 20 °C

2: hydrogenchloride / tetrahydrofuran

With pyridine; hydrogenchloride; trichlorophosphate; In tetrahydrofuran;
DOI:10.1021/ja902140m