1-(3-bromo-4-chlorophenyl)-N-((R)-1-(3-chlorophenyl)ethyl)ethanamine

Base Information

• Chemical Name: 1-(3-bromo-4-chlorophenyl)-N-((R)-1-(3-chlorophenyl)ethyl)ethanamine
• CAS No.: 1025772-35-3
• Molecular Formula: C₁₆H₁₆BrCl₂N
• Molecular Weight: 373.12
• Mol file: 1025772-35-3.mol

Synonyms:1-(3-bromo-4-chlorophenyl)-N-((R)-1-(3-chlorophenyl)ethyl)ethanamine

Chemical Property of 1-(3-bromo-4-chlorophenyl)-N-((R)-1-(3-chlorophenyl)ethyl)ethanamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(3-bromo-4-chlorophenyl)-N-((R)-1-(3-chlorophenyl)ethyl)ethanamine

There total 1 articles about 1-(3-bromo-4-chlorophenyl)-N-((R)-1-(3-chlorophenyl)ethyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

1-(3-bromo-4-chlorophenyl)ethan-1-one (54826-14-1) + (R)-α-(m-chlorophenyl)ethylamine (24358-43-8,68297-62-1,147200-14-4,17061-53-9) → 1-(3-bromo-4-chlorophenyl)-N-((R)-1-(3-chlorophenyl)ethyl)ethanamine (1025772-35-3)

Guidance literature:

1-(3-bromo-4-chlorophenyl)ethan-1-one; (R)-α-(m-chlorophenyl)ethylamine; With triethylamine; titanium tetrachloride; In 1,2-dichloro-ethane; at -78 - 20 ℃; for 10h;

With sodium cyanoborohydride; In methanol; 1,2-dichloro-ethane; for 3h;

With ammonium chloride; In methanol; water; 1,2-dichloro-ethane;

Reference yield:

Benzophenone imine (1013-88-3) + 1-(3-bromo-4-chlorophenyl)-N-((R)-1-(3-chlorophenyl)ethyl)ethanamine (1025772-35-3) → C29H26Cl2N2

Guidance literature:

With sodium t-butanolate; XPhos; palladium diacetate; In toluene; at 110 ℃; for 12h;

upstream raw materials:

1-(3-bromo-4-chlorophenyl)ethan-1-one

(R)-α-(m-chlorophenyl)ethylamine