2-(4-Chloro-phenyl)-4-methyl-6-phenyl-2H-[1,2,4]triazine-3,5-dione

Base Information

• Chemical Name: 2-(4-Chloro-phenyl)-4-methyl-6-phenyl-2H-[1,2,4]triazine-3,5-dione
• CAS No.: 212574-63-5
• Molecular Formula: C₁₆H₁₂ClN₃O₂
• Molecular Weight: 313.743
• Mol file: 212574-63-5.mol

Synonyms:2-(4-Chloro-phenyl)-4-methyl-6-phenyl-2H-[1,2,4]triazine-3,5-dione

Chemical Property of 2-(4-Chloro-phenyl)-4-methyl-6-phenyl-2H-[1,2,4]triazine-3,5-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-Chloro-phenyl)-4-methyl-6-phenyl-2H-[1,2,4]triazine-3,5-dione

There total 1 articles about 2-(4-Chloro-phenyl)-4-methyl-6-phenyl-2H-[1,2,4]triazine-3,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl chloroformate (79-22-1) + 2-[(4-Chloro-phenyl)-hydrazono]-N-methyl-2-phenyl-acetamide → 2-(4-Chloro-phenyl)-4-methyl-6-phenyl-2H-[1,2,4]triazine-3,5-dione (212574-63-5)

Guidance literature:

With sodium hydride; Yield given. Multistep reaction; 1.) THF, RT, 1 h, 2.) THF, RT, 15 h;

DOI:10.1080/10426509708031566

Reference yield: 80.0%

2-(4-Chloro-phenyl)-4-methyl-6-phenyl-2H-[1,2,4]triazine-3,5-dione (212574-63-5) → 2-(4-Chloro-phenyl)-4-methyl-6-phenyl-5-thioxo-4,5-dihydro-2H-[1,2,4]triazin-3-one (212574-69-1)

Guidance literature:

With tetraphosphorus decasulfide; In tetralin; at 180 ℃; for 6h;

DOI:10.1080/10426509708031566

Reference yield:

2-(4-Chloro-phenyl)-4-methyl-6-phenyl-2H-[1,2,4]triazine-3,5-dione (212574-63-5) → 2-(4-Chloro-phenyl)-4-methyl-6-phenyl-2H-[1,2,4]triazine-3,5-dithione

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / P₄S₁₀ / 1,2,3,4-tetrahydro-naphthalene / 6 h / 180 °C

2: 58 percent / P₄S₁₀ / 1,2,3,4-tetrahydro-naphthalene / 6 h / 200 °C

With tetraphosphorus decasulfide; In tetralin;

DOI:10.1080/10426509708031566

upstream raw materials:

methyl chloroformate

Downstream raw materials:

2-(4-Chloro-phenyl)-4-methyl-6-phenyl-5-thioxo-4,5-dihydro-2H-[1,2,4]triazin-3-one