thioacetic acid S-[4-(4-{bis-[4-(4-acetylsulfanyl-phenylethynyl)-phenyl]-[4-(4-trimethylsilanylethynyl-phenylethynyl)-phenyl]-silanyl}-phenylethynyl)-phenyl] ester

Base Information

• Chemical Name: thioacetic acid S-[4-(4-{bis-[4-(4-acetylsulfanyl-phenylethynyl)-phenyl]-[4-(4-trimethylsilanylethynyl-phenylethynyl)-phenyl]-silanyl}-phenylethynyl)-phenyl] ester
• CAS No.: 222417-75-6
• Molecular Formula: C₆₇H₅₀O₃S₃Si₂
• Molecular Weight: 1055.5

Synonyms:thioacetic acid S-[4-(4-{bis-[4-(4-acetylsulfanyl-phenylethynyl)-phenyl]-[4-(4-trimethylsilanylethynyl-phenylethynyl)-phenyl]-silanyl}-phenylethynyl)-phenyl] ester

Chemical Property of thioacetic acid S-[4-(4-{bis-[4-(4-acetylsulfanyl-phenylethynyl)-phenyl]-[4-(4-trimethylsilanylethynyl-phenylethynyl)-phenyl]-silanyl}-phenylethynyl)-phenyl] ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of thioacetic acid S-[4-(4-{bis-[4-(4-acetylsulfanyl-phenylethynyl)-phenyl]-[4-(4-trimethylsilanylethynyl-phenylethynyl)-phenyl]-silanyl}-phenylethynyl)-phenyl] ester

There total 6 articles about thioacetic acid S-[4-(4-{bis-[4-(4-acetylsulfanyl-phenylethynyl)-phenyl]-[4-(4-trimethylsilanylethynyl-phenylethynyl)-phenyl]-silanyl}-phenylethynyl)-phenyl] ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

1-iodo-4-(trimethylsilylethynyl)benzene (134856-58-9) + thioacetic acid S-(4-{4-[bis-[4-(4-acetylsulfanyl-phenylethynyl)-phenyl]-(4-ethynyl-phenyl)-silanyl]-phenylethynyl}-phenyl) ester (222417-73-4) → thioacetic acid S-[4-(4-{bis-[4-(4-acetylsulfanyl-phenylethynyl)-phenyl]-[4-(4-trimethylsilanylethynyl-phenylethynyl)-phenyl]-silanyl}-phenylethynyl)-phenyl] ester (222417-75-6)

Guidance literature:

With copper(l) iodide; N-ethyl-N,N-diisopropylamine; triphenylphosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran; for 24h; Ambient temperature;

DOI:10.1021/jo982085g

Reference yield:

para-diiodobenzene (624-38-4,1032416-46-8) → thioacetic acid S-[4-(4-{bis-[4-(4-acetylsulfanyl-phenylethynyl)-phenyl]-[4-(4-trimethylsilanylethynyl-phenylethynyl)-phenyl]-silanyl}-phenylethynyl)-phenyl] ester (222417-75-6)

Guidance literature:

Multi-step reaction with 5 steps

1: 1.) n-BuLi / 1.) ether, hexane, 1 h, -78 deg C, 2.) ether, -78 deg C, 30 min, then room temp., 3 h

2: 1.) t-BuLi / 1.) ether, pentane, -78 deg C, 45 min, 2.) ether, pentane, THF, -78 deg C, 1.5 h

3: 42 percent / Pd(dba)2. PPh₃, CuI_. i-Pr₂NEt / tetrahydrofuran / 72 h / Ambient temperature

4: 100 percent / Bu₄NF, Ac₂O, AcOH / tetrahydrofuran / 0.83 h

5: 69 percent / Pd(dba)2, PPh₃, CuI, i-Pr₂NEt / tetrahydrofuran / 24 h / Ambient temperature

With copper(l) iodide; n-butyllithium; Pd(dba)2*Ph₃P; tetrabutyl ammonium fluoride; tert.-butyl lithium; acetic anhydride; acetic acid; N-ethyl-N,N-diisopropylamine; triphenylphosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran;

DOI:10.1021/jo982085g

Reference yield:

4-[tris(4-iodophenyl)silyl](oxyethyl) (222417-70-1) → thioacetic acid S-[4-(4-{bis-[4-(4-acetylsulfanyl-phenylethynyl)-phenyl]-[4-(4-trimethylsilanylethynyl-phenylethynyl)-phenyl]-silanyl}-phenylethynyl)-phenyl] ester (222417-75-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) t-BuLi / 1.) ether, pentane, -78 deg C, 45 min, 2.) ether, pentane, THF, -78 deg C, 1.5 h

2: 42 percent / Pd(dba)2. PPh₃, CuI_. i-Pr₂NEt / tetrahydrofuran / 72 h / Ambient temperature

3: 100 percent / Bu₄NF, Ac₂O, AcOH / tetrahydrofuran / 0.83 h

4: 69 percent / Pd(dba)2, PPh₃, CuI, i-Pr₂NEt / tetrahydrofuran / 24 h / Ambient temperature

With copper(l) iodide; Pd(dba)2*Ph₃P; tetrabutyl ammonium fluoride; tert.-butyl lithium; acetic anhydride; acetic acid; N-ethyl-N,N-diisopropylamine; triphenylphosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran;

DOI:10.1021/jo982085g

upstream raw materials:

1-iodo-4-(trimethylsilylethynyl)benzene

thioacetic acid S-(4-{4-[bis-[4-(4-acetylsulfanyl-phenylethynyl)-phenyl]-(4-ethynyl-phenyl)-silanyl]-phenylethynyl}-phenyl) ester

para-diiodobenzene

4-[tris(4-iodophenyl)silyl](oxyethyl)

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 222417-75-6 thioacetic acid S-[4-(4-{bis-[4-(4-acetylsulfanyl-phenylethynyl)-phenyl]-[4-(4-trimethylsilanylethynyl-phenylethynyl)-phenyl]-silanyl}-phenylethynyl)-phenyl] ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send