5-Propyl-1-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-pyrazole-3-carboxylic Acid

Base Information

Chemical Name:5-Propyl-1-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-pyrazole-3-carboxylic Acid
CAS No.:1260231-37-5
Molecular Formula:C₂₁H₂₀N₆O₂
Molecular Weight:388.429
Hs Code.:

Synonyms:5-Propyl-1-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-pyrazole-3-carboxylic Acid

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Chemical Property of 5-Propyl-1-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-pyrazole-3-carboxylic Acid

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Technology Process of 5-Propyl-1-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-pyrazole-3-carboxylic Acid

There total 1 articles about 5-Propyl-1-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-pyrazole-3-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-(tetrazol-5'-yl)phenylboronic acid

: 1260231-34-2
1-(4-bromobenzyl)-5-propyl-1H-pyrazole-3-carboxylic acid ethyl ester

: 1260231-37-5
5-Propyl-1-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-pyrazole-3-carboxylic Acid

Guidance literature:: 2-(tetrazol-5'-yl)phenylboronic acid; 1-(4-bromobenzyl)-5-propyl-1H-pyrazole-3-carboxylic acid ethyl ester; With water; sodium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In methanol; at 90 ℃; for 2h; Inert atmosphere; Microwave irradiation;

With hydrogenchloride; In water; pH=3 - 4;

Reference yield:

: 138165-77-2,460039-42-3
(R)-3-amino-4-phenylbutanoic acid hydrochloride

: 1260231-37-5
5-Propyl-1-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-pyrazole-3-carboxylic Acid

: 1260231-39-7
(R)-4-Phenyl-3-({5-propyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1H-pyrazole-3-carbonyl}amino)butyric Acid

Guidance literature:: 5-Propyl-1-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-pyrazole-3-carboxylic Acid; With 2,6-dimethylpyridine; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 0.5h;

(R)-3-amino-4-phenylbutanoic acid hydrochloride; In dichloromethane; at 0 - 20 ℃;