4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-(3-methylisoxazol-5-yl)methoxybenzamide

Base Information

• Chemical Name: 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-(3-methylisoxazol-5-yl)methoxybenzamide
• CAS No.: 102670-57-5
• Molecular Formula: C₁₈H₂₅ClN₄O₃
• Molecular Weight: 380.874
• Mol file: 102670-57-5.mol

Synonyms:4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-(3-methylisoxazol-5-yl)methoxybenzamide

Chemical Property of 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-(3-methylisoxazol-5-yl)methoxybenzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-(3-methylisoxazol-5-yl)methoxybenzamide

There total 2 articles about 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-(3-methylisoxazol-5-yl)methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

5-(bromomethyl)-3-methyl-1,2-oxazole (36958-61-9) + tetra-n-butylammonium salt of 4-amino-5-chloro-N-<2-(diethylamino)ethyl>-2-hydroxybenzamide (102670-98-4) → 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-(3-methylisoxazol-5-yl)methoxybenzamide (102670-57-5)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 2h;

DOI:10.1021/jm00403a011

Reference yield: 87.0%

→ 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-(3-methylisoxazol-5-yl)methoxybenzamide (102670-57-5)

Guidance literature:

upstream raw materials:

5-(bromomethyl)-3-methyl-1,2-oxazole

tetra-n-butylammonium salt of 4-amino-5-chloro-N-<2-(diethylamino)ethyl>-2-hydroxybenzamide