3-(5-methoxy-2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonylamino)phenoxy)benzamidine

Base Information

Chemical Name:3-(5-methoxy-2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonylamino)phenoxy)benzamidine
CAS No.:330939-49-6
Molecular Formula:C₂₇H₂₄N₄O₅S
Molecular Weight:516.577
Hs Code.:

Synonyms:3-(5-methoxy-2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonylamino)phenoxy)benzamidine

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Chemical Property of 3-(5-methoxy-2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonylamino)phenoxy)benzamidine

Chemical Property:

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Technology Process of 3-(5-methoxy-2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonylamino)phenoxy)benzamidine

There total 8 articles about 3-(5-methoxy-2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonylamino)phenoxy)benzamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 476352-55-3
2'-tert-butylsulfamoyl-biphenyl-4-carboxylic acid [2-(3-cyano-phenoxy)-4-methoxy-phenyl]-amide

: 330939-49-6
3-(5-methoxy-2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonylamino)phenoxy)benzamidine

Guidance literature:: 2'-tert-butylsulfamoyl-biphenyl-4-carboxylic acid [2-(3-cyano-phenoxy)-4-methoxy-phenyl]-amide; With hydrogenchloride; In methanol;

With ammonium acetate; In methanol;
DOI:10.1016/S0960-894X(02)00234-2

Reference yield:

: 446-38-8
2-fluoro-4-methoxy-1-nitro-benzene

: 330939-49-6
3-(5-methoxy-2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonylamino)phenoxy)benzamidine

Guidance literature:: Multi-step reaction with 4 steps

1.1: K₂CO₃ / dimethylformamide

2.1: SnCl₂*2H₂O / ethyl acetate

3.1: BOP; Et₃N / dimethylformamide

4.1: HCl (g) / methanol

4.2: NH₄OAc / methanol

With hydrogenchloride; potassium carbonate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; tin(ll) chloride; In methanol; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(02)00234-2

Reference yield:

: 873-62-1
m-cyanophenol

: 330939-49-6
3-(5-methoxy-2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonylamino)phenoxy)benzamidine

Guidance literature:: Multi-step reaction with 4 steps

1.1: K₂CO₃ / dimethylformamide

2.1: SnCl₂*2H₂O / ethyl acetate

3.1: BOP; Et₃N / dimethylformamide

4.1: HCl (g) / methanol

4.2: NH₄OAc / methanol

With hydrogenchloride; potassium carbonate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; tin(ll) chloride; In methanol; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(02)00234-2