methyl 4-benzyloxy-5-chloro-2-(5'-hydroxy-2'-methoxy-4'-methoxycarbonyl-3',6'-dimethylphenoxy)-6-methylbenzoate

Base Information

• Chemical Name: methyl 4-benzyloxy-5-chloro-2-(5'-hydroxy-2'-methoxy-4'-methoxycarbonyl-3',6'-dimethylphenoxy)-6-methylbenzoate
• CAS No.: 164405-55-4
• Molecular Formula: C₂₇H₂₇ClO₈
• Molecular Weight: 514.96
• Mol file: 164405-55-4.mol

Synonyms:methyl 4-benzyloxy-5-chloro-2-(5'-hydroxy-2'-methoxy-4'-methoxycarbonyl-3',6'-dimethylphenoxy)-6-methylbenzoate

Chemical Property of methyl 4-benzyloxy-5-chloro-2-(5'-hydroxy-2'-methoxy-4'-methoxycarbonyl-3',6'-dimethylphenoxy)-6-methylbenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of methyl 4-benzyloxy-5-chloro-2-(5'-hydroxy-2'-methoxy-4'-methoxycarbonyl-3',6'-dimethylphenoxy)-6-methylbenzoate

There total 1 articles about methyl 4-benzyloxy-5-chloro-2-(5'-hydroxy-2'-methoxy-4'-methoxycarbonyl-3',6'-dimethylphenoxy)-6-methylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + 4-benzyloxy-5-chloro-2-(5'-hydroxy-2'-methoxy-4'-methoxycarbonyl-3',6'-dimethylphenoxy)-6-methylbenzoic acid → methyl 4-benzyloxy-5-chloro-2-(5'-hydroxy-2'-methoxy-4'-methoxycarbonyl-3',6'-dimethylphenoxy)-6-methylbenzoate (164405-55-4)

Guidance literature:

In methanol; diethyl ether; at 0 ℃; for 0.05h;

DOI:10.1071/CH9950635

Reference yield: 88.0%

methyl 4-benzyloxy-5-chloro-2-(5'-hydroxy-2'-methoxy-4'-methoxycarbonyl-3',6'-dimethylphenoxy)-6-methylbenzoate (164405-55-4) → methyl 5-chloro-4-hydroxy-2-(5'-hydroxy-2'-methoxy-4'-methoxycarbonyl-3',6'-dimethylphenoxy)-6-methylbenzoate

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; for 36h; Ambient temperature;

DOI:10.1071/CH9950635

Reference yield: 88.0%

methyl 4-benzyloxy-5-chloro-2-(5'-hydroxy-2'-methoxy-4'-methoxycarbonyl-3',6'-dimethylphenoxy)-6-methylbenzoate (164405-55-4) → methyl 5-chloro-2-(2',4'-dihydroxy-5'-methoxycarbonyl-3',6'-dimethylphenoxy)-4-hydroxy-6-methylbenzoate

Guidance literature:

With boron trichloride; In dichloromethane; for 12h; Ambient temperature;

DOI:10.1071/CH9950635

upstream raw materials:

diazomethane