Tricyclo[4.2.0.01,4]octane-7-carboxylic acid, (1S*,4alpha,6beta,7beta)- (9CI)

Base Information

• Chemical Name: Tricyclo[4.2.0.01,4]octane-7-carboxylic acid, (1S*,4alpha,6beta,7beta)- (9CI)
• CAS No.: 75888-99-2
• Molecular Formula: C₉H₁₂O₂
• Molecular Weight: 152.193
• Mol file: 75888-99-2.mol

Synonyms:Tricyclo[4.2.0.01,4]octane-7-carboxylic acid, (1S*,4alpha,6beta,7beta)- (9CI)

Chemical Property of Tricyclo[4.2.0.01,4]octane-7-carboxylic acid, (1S*,4alpha,6beta,7beta)- (9CI)

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Tricyclo[4.2.0.01,4]octane-7-carboxylic acid, (1S*,4alpha,6beta,7beta)- (9CI)

There total 2 articles about Tricyclo[4.2.0.01,4]octane-7-carboxylic acid, (1S*,4alpha,6beta,7beta)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl tricyclo<4.2.0.01,4>octane-3-carboxylate (75888-97-0,75918-58-0) → exo-tricyclo<4.2.0.01,4>octane-3-carboxylic acid (75888-99-2,75918-53-5)

Guidance literature:

With potassium hydroxide; In methanol; at 60 ℃; Yield given;

DOI:10.1021/ja00545a012

Reference yield:

methyl tricyclo<4.2.0.01,4>octane-3-carboxylate (75888-97-0,75918-58-0) → endo-tricyclo<4.2.0.01,4>octane-3-carboxylic acid (75888-99-2,75918-53-5)

Guidance literature:

With potassium hydroxide; at 65 ℃; Yield given;

DOI:10.1021/ja00545a012

Reference yield: 92.0%

methyllithium (917-54-4) + tricyclo<4.2.0.01,4>octane-3-carboxylic acid (75888-99-2,75918-53-5) → (1R,4R,6S)-1-Tricyclo[4.2.0.01,4]oct-3-yl-ethanone (75889-00-8,75918-52-4)

Guidance literature:

In diethyl ether; hexane; for 1h; Ambient temperature;

DOI:10.1021/ja00545a012

upstream raw materials:

methyl tricyclo<4.2.0.0^1,4>octane-3-carboxylate

Downstream raw materials:

(1R,4R,6S)-1-Tricyclo[4.2.0.0^1,4]oct-3-yl-ethanone

p-bromoanilide of endo-tricyclo<4.2.0.0^1,4>octane-3-carboxylic acid

p-bromoanilide of exo-tricyclo<4.2.0.0^1,4>octane-3-carboxylic acid

(1R,3S,4R,6S)-1-Tricyclo[4.2.0.0^1,4]oct-3-yl-ethanone