(4R)-4-(hydrazine-N,N'-dicarboxylic acid diethyl ester)-5-phenylpent-2-E-enal

Base Information

• Chemical Name: (4R)-4-(hydrazine-N,N'-dicarboxylic acid diethyl ester)-5-phenylpent-2-E-enal
• CAS No.: 913698-95-0
• Molecular Formula: C₁₇H₂₂N₂O₅
• Molecular Weight: 334.372
• Mol file: 913698-95-0.mol

Synonyms:(4R)-4-(hydrazine-N,N'-dicarboxylic acid diethyl ester)-5-phenylpent-2-E-enal

Chemical Property of (4R)-4-(hydrazine-N,N'-dicarboxylic acid diethyl ester)-5-phenylpent-2-E-enal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4R)-4-(hydrazine-N,N'-dicarboxylic acid diethyl ester)-5-phenylpent-2-E-enal

There total 1 articles about (4R)-4-(hydrazine-N,N'-dicarboxylic acid diethyl ester)-5-phenylpent-2-E-enal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl diazodicarboxylate (4143-61-7,218603-74-8) + (2E)-5-phenyl-2-pentenal (33046-84-3,112087-56-6,37868-70-5) → (4R)-4-(hydrazine-N,N'-dicarboxylic acid diethyl ester)-5-phenylpent-2-E-enal (913698-95-0) + (4S)-4-(hydrazine-N,N'-dicarboxylic acid diethyl ester)-5-phenylpent-2-E-enal

Guidance literature:

With benzoic acid; 2-[bis(3,5-bis-triF-Me-Phe)-tri-Me-silanyloxy-Me]pyrrolidine; In toluene; for 4h; Title compound not separated from byproducts.;

DOI:10.1021/ja064637f

Reference yield:

(4R)-4-(hydrazine-N,N'-dicarboxylic acid diethyl ester)-5-phenylpent-2-E-enal (913698-95-0) → C17H24N2O5

Guidance literature:

With sodium tetrahydroborate; In methanol; for 0.5h;

DOI:10.1021/ja064637f

Reference yield:

(4R)-4-(hydrazine-N,N'-dicarboxylic acid diethyl ester)-5-phenylpent-2-E-enal (913698-95-0) → p-chlorobenzoic acid 4-(hydrazine-N,N'-dicarboxylic acid diethyl ester)-5-phenylpent-2-E-enyl ester

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄ / methanol / 0.5 h

2: Et₃N / CH₂Cl₂

With sodium tetrahydroborate; triethylamine; In methanol; dichloromethane;

DOI:10.1021/ja064637f

upstream raw materials:

diethyl diazodicarboxylate

(2E)-5-phenyl-2-pentenal