(R,S)-1,2,5,7-Tetrahydro-4-methyl-5-oxo-2-<(2-trifluoromethyl)phenyl>furo<3,4-b>pyridin-3-carbonsaeuremethylester

Base Information

• Chemical Name: (R,S)-1,2,5,7-Tetrahydro-4-methyl-5-oxo-2-<(2-trifluoromethyl)phenyl>furo<3,4-b>pyridin-3-carbonsaeuremethylester
• CAS No.: 138486-21-2
• Molecular Formula: C₁₇H₁₄F₃NO₄
• Molecular Weight: 353.298
• Mol file: 138486-21-2.mol

Synonyms:(R,S)-1,2,5,7-Tetrahydro-4-methyl-5-oxo-2-<(2-trifluoromethyl)phenyl>furo<3,4-b>pyridin-3-carbonsaeuremethylester

Chemical Property of (R,S)-1,2,5,7-Tetrahydro-4-methyl-5-oxo-2-<(2-trifluoromethyl)phenyl>furo<3,4-b>pyridin-3-carbonsaeuremethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R,S)-1,2,5,7-Tetrahydro-4-methyl-5-oxo-2-<(2-trifluoromethyl)phenyl>furo<3,4-b>pyridin-3-carbonsaeuremethylester

There total 1 articles about (R,S)-1,2,5,7-Tetrahydro-4-methyl-5-oxo-2-<(2-trifluoromethyl)phenyl>furo<3,4-b>pyridin-3-carbonsaeuremethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

(R,S)-1,2-Dihydro-4,6-dimethyl-2-<2-(trifluormethyl)phenyl>-pyridin-3,5-dicarbonsaeuredimethylester (137481-59-5) → (R,S)-1,2,5,7-Tetrahydro-4-methyl-5-oxo-2-<(2-trifluoromethyl)phenyl>furo<3,4-b>pyridin-3-carbonsaeuremethylester (138486-21-2) + 4,6-Dimethyl-2-<2-(trifluormethyl)phenyl>-pyridin-3,5-dicarbonsaeuredimethylester (137481-65-3)

Guidance literature:

With pyridine; pyridinium hydrobromide perbromide; In chloroform; 1) 30 min, 0 deg C, 2) 90 min, reflux;

DOI:10.1002/ardp.2503241111

Reference yield: 60.0%

(R,S)-1,2,5,7-Tetrahydro-4-methyl-5-oxo-2-<(2-trifluoromethyl)phenyl>furo<3,4-b>pyridin-3-carbonsaeuremethylester (138486-21-2) → 5,7-Dihydro-4-methyl-5-oxo-2-<(2-trifluoromethyl)phenyl>furo<3,4-b>pyridin-3-carbonsaeuremethylester (138486-22-3)

Guidance literature:

With manganese(IV) oxide; In toluene; Heating;

DOI:10.1002/ardp.2503241111

upstream raw materials:

(R,S)-1,2-Dihydro-4,6-dimethyl-2-<2-(trifluormethyl)phenyl>-pyridin-3,5-dicarbonsaeuredimethylester

Downstream raw materials:

5,7-Dihydro-4-methyl-5-oxo-2-<(2-trifluoromethyl)phenyl>furo<3,4-b>pyridin-3-carbonsaeuremethylester