dimethyl 3-(formylamino)-5-phenyl-4,5-dihydro-3H-pyrazole-3-phosphonate

Base Information

• Chemical Name: dimethyl 3-(formylamino)-5-phenyl-4,5-dihydro-3H-pyrazole-3-phosphonate
• CAS No.: 1348705-17-8
• Molecular Formula: C₁₂H₁₆N₃O₄P
• Molecular Weight: 297.25
• Mol file: 1348705-17-8.mol

Synonyms:dimethyl 3-(formylamino)-5-phenyl-4,5-dihydro-3H-pyrazole-3-phosphonate

Chemical Property of dimethyl 3-(formylamino)-5-phenyl-4,5-dihydro-3H-pyrazole-3-phosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethyl 3-(formylamino)-5-phenyl-4,5-dihydro-3H-pyrazole-3-phosphonate

There total 1 articles about dimethyl 3-(formylamino)-5-phenyl-4,5-dihydro-3H-pyrazole-3-phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

dimethyl 1-(formylamino)ethylene-phosphonate + phenyldiazomethane (908094-04-2) → dimethyl 3-(formylamino)-5-phenyl-4,5-dihydro-3H-pyrazole-3-phosphonate (1348705-17-8)

Guidance literature:

In diethyl ether; at 20 ℃; for 24h;

DOI:10.1016/j.tet.2011.10.010

Reference yield: 93.0%

dimethyl 3-(formylamino)-5-phenyl-4,5-dihydro-3H-pyrazole-3-phosphonate (1348705-17-8) → dimethyl (5-phenyl-1H-pyrazol-3-yl)phosphonate (68204-13-7)

Guidance literature:

dimethyl 3-(formylamino)-5-phenyl-4,5-dihydro-3H-pyrazole-3-phosphonate; With methanol; chloro-trimethyl-silane; at 20 ℃; for 5h;

With sodium hydrogencarbonate; In water;

DOI:10.1016/j.tet.2011.10.010

Reference yield: 63.0%

dimethyl 3-(formylamino)-5-phenyl-4,5-dihydro-3H-pyrazole-3-phosphonate (1348705-17-8) → (1RS,2RS)-1-amino-2-phenylcyclopropanephosphonic acid

Guidance literature:

dimethyl 3-(formylamino)-5-phenyl-4,5-dihydro-3H-pyrazole-3-phosphonate; In toluene; for 3h; Reflux;

With hydrogenchloride; In water; for 6h; Reflux;

With methyloxirane; In methanol; at 30 ℃;

DOI:10.1016/j.tet.2011.10.010

upstream raw materials:

phenyldiazomethane

Downstream raw materials:

dimethyl (5-phenyl-1H-pyrazol-3-yl)phosphonate