Technology Process of (R)-(E)-1-(dimethylphenylsilyl)-1-phenyl-2-butene
There total 3 articles about (R)-(E)-1-(dimethylphenylsilyl)-1-phenyl-2-butene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C30H32OSi2;
With
1,1,3,3-tetramethylbutane isonitrile;
palladium(II) acetylacetonate;
In
toluene;
for 1h;
Heating;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at 0 ℃;
for 0.25h;
DOI:10.1002/chem.200401031
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: Et3N; 4-dimethylaminopyridine / tetrahydrofuran / 20 °C
2.1: 1,1,3,3-tetramethylbutyl isocyanide / [Pd(acac)2] / toluene / 1 h / Heating
2.2: 92 percent / n-BuLi / tetrahydrofuran; hexane / 0.25 h / 0 °C
With
dmap; 1,1,3,3-tetramethylbutane isonitrile; triethylamine;
palladium(II) acetylacetonate;
In
tetrahydrofuran; toluene;
DOI:10.1002/chem.200401031
- Guidance literature:
-
With
palladium(II) acetylacetonate; 1,1,3,3-tetramethylbutane isonitrile; phenyllithium;
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
1.) toluene, reflux, 2 h, 2.) THF, 0 deg C, 0.5 h;
DOI:10.1021/ja954251x
