6,9-dimethyl-2-(4-methylphenyl)-7,8-diphenyl-5,6,9,10-tetrahydro-6,9-methano-1H-<1,2,4>-triazolo<1,2-b>phthalazine-1,3,12(2H)-trione

Base Information

• Chemical Name: 6,9-dimethyl-2-(4-methylphenyl)-7,8-diphenyl-5,6,9,10-tetrahydro-6,9-methano-1H-<1,2,4>-triazolo<1,2-b>phthalazine-1,3,12(2H)-trione
• CAS No.: 95930-80-6
• Molecular Formula: C₃₂H₂₇N₃O₃
• Molecular Weight: 501.585
• Mol file: 95930-80-6.mol

Synonyms:6,9-dimethyl-2-(4-methylphenyl)-7,8-diphenyl-5,6,9,10-tetrahydro-6,9-methano-1H-<1,2,4>-triazolo<1,2-b>phthalazine-1,3,12(2H)-trione

Chemical Property of 6,9-dimethyl-2-(4-methylphenyl)-7,8-diphenyl-5,6,9,10-tetrahydro-6,9-methano-1H-<1,2,4>-triazolo<1,2-b>phthalazine-1,3,12(2H)-trione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6,9-dimethyl-2-(4-methylphenyl)-7,8-diphenyl-5,6,9,10-tetrahydro-6,9-methano-1H-<1,2,4>-triazolo<1,2-b>phthalazine-1,3,12(2H)-trione

There total 3 articles about 6,9-dimethyl-2-(4-methylphenyl)-7,8-diphenyl-5,6,9,10-tetrahydro-6,9-methano-1H-<1,2,4>-triazolo<1,2-b>phthalazine-1,3,12(2H)-trione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-dimethyl-3,4-diphenylcyclopenta-2,4-dienone (26307-17-5) → 6,9-dimethyl-2-(4-methylphenyl)-7,8-diphenyl-5,6,9,10-tetrahydro-6,9-methano-1H-<1,2,4>-triazolo<1,2-b>phthalazine-1,3,12(2H)-trione (95930-80-6)

Guidance literature:

Multi-step reaction with 3 steps

1: benzene / 36 h / 105 °C

2: KF / dimethylformamide / 24 h / 80 °C

3: CDCl₃ / 0.08 h / -40 °C

With potassium fluoride; In chloroform-d1; N,N-dimethyl-formamide; benzene;

DOI:10.1039/c39840001675

Reference yield:

(1S,4R,5R,6R)-5,6-Bis-bromomethyl-1,4-dimethyl-2,3-diphenyl-bicyclo[2.2.1]hept-2-en-7-one → 6,9-dimethyl-2-(4-methylphenyl)-7,8-diphenyl-5,6,9,10-tetrahydro-6,9-methano-1H-<1,2,4>-triazolo<1,2-b>phthalazine-1,3,12(2H)-trione (95930-80-6)

Guidance literature:

Multi-step reaction with 2 steps

1: KF / dimethylformamide / 24 h / 80 °C

2: CDCl₃ / 0.08 h / -40 °C

With potassium fluoride; In chloroform-d1; N,N-dimethyl-formamide;

DOI:10.1039/c39840001675

Reference yield:

4-(4-Methylphenyl)-1,2,4-triazoline-3,5-dione (72708-83-9) + 5,6-dimethylene-1,4-dimethyl-2,3-diphenylnorborn-2-en-7-one → 6,9-dimethyl-2-(4-methylphenyl)-7,8-diphenyl-5,6,9,10-tetrahydro-6,9-methano-1H-<1,2,4>-triazolo<1,2-b>phthalazine-1,3,12(2H)-trione (95930-80-6)

Guidance literature:

In chloroform-d1; at -40 ℃; for 0.0833333h;

DOI:10.1039/c39840001675

upstream raw materials:

4-(4-Methylphenyl)-1,2,4-triazoline-3,5-dione

2,5-dimethyl-3,4-diphenylcyclopenta-2,4-dienone