N-[3-bromo-4-(3-[⁽¹⁸⁾F]-fluoropropoxy)-benzyl]-guanidine hydrochloride

Base Information

• Chemical Name: N-[3-bromo-4-(3-[⁽¹⁸⁾F]-fluoropropoxy)-benzyl]-guanidine hydrochloride
• CAS No.: 1037078-71-9
• Molecular Formula: C₁₁H₁₅BrFN₃O*ClH
• Molecular Weight: 339.625

Synonyms:N-[3-bromo-4-(3-[⁽¹⁸⁾F]-fluoropropoxy)-benzyl]-guanidine hydrochloride

Chemical Property of N-[3-bromo-4-(3-[⁽¹⁸⁾F]-fluoropropoxy)-benzyl]-guanidine hydrochloride

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Technology Process of N-[3-bromo-4-(3-[⁽¹⁸⁾F]-fluoropropoxy)-benzyl]-guanidine hydrochloride

There total 1 articles about N-[3-bromo-4-(3-[⁽¹⁸⁾F]-fluoropropoxy)-benzyl]-guanidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(18)F-fluoropropyl toluenesulfonate + 1,3-bis(tert-butoxy-carbonyl)-[3-bromo-4-hydroxy-benzyl]-guanidine (1037079-11-0) → N-[3-bromo-4-(3-[(18)F]-fluoropropoxy)-benzyl]-guanidine hydrochloride (1037078-71-9)

Guidance literature:

3-⁽¹⁸⁾F-fluoropropyl toluenesulfonate; 1,3-bis(tert-butoxy-carbonyl)-[3-bromo-4-hydroxy-benzyl]-guanidine; With potassium carbonate; In acetonitrile; at 80 ℃; for 0.75h;

With hydrogenchloride; In 1,4-dioxane; acetonitrile; at 50 ℃; for 0.25h;

upstream raw materials:

1,3-bis(tert-butoxy-carbonyl)-[3-bromo-4-hydroxy-benzyl]-guanidine

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