Technology Process of 2-azidophenyl 4-tolylmethyl ketone
There total 6 articles about 2-azidophenyl 4-tolylmethyl ketone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) EtMgBr / 1.) Et2O, 2 h, reflux; 2.) Et2O, 30 min
2: 1.) BH3*SMe2, 2.) CH3OH / 1.) THF, 0 deg C, 2 h; r.t., 2 h, 2.) THF, 1 h, reflux
3: 81 percent / O3/O2 / ethyl acetate / 10 h
4: 76 percent / 5M HCl / ethanol / 3 h / Heating
5: 1.) NaNO2, 10M HCl, 2.) NaN3 / 1.)H2O, 0 deg C, 30 min, 2.) H2O, 10 min
With
hydrogenchloride; methanol; sodium azide; dimethylsulfide borane complex; ethylmagnesium bromide; oxygen; ozone; sodium nitrite;
In
ethanol; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) BH3*SMe2, 2.) CH3OH / 1.) THF, 0 deg C, 2 h; r.t., 2 h, 2.) THF, 1 h, reflux
2: 81 percent / O3/O2 / ethyl acetate / 10 h
3: 76 percent / 5M HCl / ethanol / 3 h / Heating
4: 1.) NaNO2, 10M HCl, 2.) NaN3 / 1.)H2O, 0 deg C, 30 min, 2.) H2O, 10 min
With
hydrogenchloride; methanol; sodium azide; dimethylsulfide borane complex; oxygen; ozone; sodium nitrite;
In
ethanol; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) EtMgBr / 1.) Et2O, 2 h, reflux; 2.) Et2O, 30 min
2: 1.) BH3*SMe2, 2.) CH3OH / 1.) THF, 0 deg C, 2 h; r.t., 2 h, 2.) THF, 1 h, reflux
3: 81 percent / O3/O2 / ethyl acetate / 10 h
4: 76 percent / 5M HCl / ethanol / 3 h / Heating
5: 1.) NaNO2, 10M HCl, 2.) NaN3 / 1.)H2O, 0 deg C, 30 min, 2.) H2O, 10 min
With
hydrogenchloride; methanol; sodium azide; dimethylsulfide borane complex; ethylmagnesium bromide; oxygen; ozone; sodium nitrite;
In
ethanol; ethyl acetate;
