1-(4-methoxyphenyl)-3-(4-methyloxazol-2-yl)-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-1,4,5,6-tetrahydropyrazolo[3,4-c]pyridin-7-one

Base Information

Chemical Name:1-(4-methoxyphenyl)-3-(4-methyloxazol-2-yl)-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-1,4,5,6-tetrahydropyrazolo[3,4-c]pyridin-7-one
CAS No.:503612-83-7
Molecular Formula:C₂₈H₂₃N₅O₄
Molecular Weight:493.522
Hs Code.:

Synonyms:1-(4-methoxyphenyl)-3-(4-methyloxazol-2-yl)-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-1,4,5,6-tetrahydropyrazolo[3,4-c]pyridin-7-one

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Chemical Property of 1-(4-methoxyphenyl)-3-(4-methyloxazol-2-yl)-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-1,4,5,6-tetrahydropyrazolo[3,4-c]pyridin-7-one

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Technology Process of 1-(4-methoxyphenyl)-3-(4-methyloxazol-2-yl)-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-1,4,5,6-tetrahydropyrazolo[3,4-c]pyridin-7-one

There total 6 articles about 1-(4-methoxyphenyl)-3-(4-methyloxazol-2-yl)-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-1,4,5,6-tetrahydropyrazolo[3,4-c]pyridin-7-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

: C₂₈H₂₂ClN₅O₄

: 503612-83-7
1-(4-methoxyphenyl)-3-(4-methyloxazol-2-yl)-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-1,4,5,6-tetrahydropyrazolo[3,4-c]pyridin-7-one

Guidance literature:: With palladium 10% on activated carbon; hydrogen; for 0.3h; under 2068.65 Torr;

Reference yield:

: 473927-64-9
1-(4-methoxy-phenyl)-6-(4-iodo-phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester

: 503612-83-7
1-(4-methoxyphenyl)-3-(4-methyloxazol-2-yl)-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-1,4,5,6-tetrahydropyrazolo[3,4-c]pyridin-7-one

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate; copper(l) iodide / dimethyl sulfoxide / 24 h / 130 °C / Inert atmosphere

2: formamide; sodium methylate / N,N-dimethyl-formamide; methanol / 48 h

3: 24 h / 130 °C

4: hydrogen; palladium 10% on activated carbon / 0.3 h / 2068.65 Torr

With copper(l) iodide; palladium 10% on activated carbon; hydrogen; sodium methylate; potassium carbonate; formamide; In methanol; dimethyl sulfoxide; N,N-dimethyl-formamide;

Reference yield:

: 142-08-5
2-hydroxypyridin

: 503612-83-7
1-(4-methoxyphenyl)-3-(4-methyloxazol-2-yl)-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-1,4,5,6-tetrahydropyrazolo[3,4-c]pyridin-7-one

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate; copper(l) iodide / dimethyl sulfoxide / 24 h / 130 °C / Inert atmosphere

2: formamide; sodium methylate / N,N-dimethyl-formamide; methanol / 48 h

3: 24 h / 130 °C

4: hydrogen; palladium 10% on activated carbon / 0.3 h / 2068.65 Torr

With copper(l) iodide; palladium 10% on activated carbon; hydrogen; sodium methylate; potassium carbonate; formamide; In methanol; dimethyl sulfoxide; N,N-dimethyl-formamide;