diethyl [[2,5-bis(2-ethylhexyloxy)-4-bromophenyl]methyl]phosphonate

Base Information

• Chemical Name: diethyl [[2,5-bis(2-ethylhexyloxy)-4-bromophenyl]methyl]phosphonate
• CAS No.: 357396-90-8
• Molecular Formula: C₂₇H₄₈BrO₅P
• Molecular Weight: 563.553
• Mol file: 357396-90-8.mol

Synonyms:diethyl [[2,5-bis(2-ethylhexyloxy)-4-bromophenyl]methyl]phosphonate

Chemical Property of diethyl [[2,5-bis(2-ethylhexyloxy)-4-bromophenyl]methyl]phosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diethyl [[2,5-bis(2-ethylhexyloxy)-4-bromophenyl]methyl]phosphonate

There total 5 articles about diethyl [[2,5-bis(2-ethylhexyloxy)-4-bromophenyl]methyl]phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-bromo-4-(bromomethyl)-2,5-bis(2-ethylhexyloxy)benzene (357396-89-5) + triethyl phosphite (122-52-1) → diethyl [[2,5-bis(2-ethylhexyloxy)-4-bromophenyl]methyl]phosphonate (357396-90-8)

Guidance literature:

at 160 ℃; for 1.5h;

DOI:10.1021/ja015614y

Reference yield:

2-methylbenzene-1,4-diol (95-71-6,96937-50-7) → diethyl [[2,5-bis(2-ethylhexyloxy)-4-bromophenyl]methyl]phosphonate (357396-90-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 66 percent / K₂CO₃ / acetonitrile / 72 h / Heating

2: 51 percent / N-bromosuccinimide; 2,2'-azobis(2-methylpropionitrile) / CCl₄ / 2 h / Heating

3: 95 percent / 2 h / 160 °C

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); potassium carbonate; In tetrachloromethane; acetonitrile; 1: Williamson etherification / 3: Michalis-Arbuzov reaction;

DOI:10.1080/15421400601021505

Reference yield:

1,4-bis(2-ethylhexyloxy)-2-methylbenzene (354123-99-2) → diethyl [[2,5-bis(2-ethylhexyloxy)-4-bromophenyl]methyl]phosphonate (357396-90-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 51 percent / N-bromosuccinimide; 2,2'-azobis(2-methylpropionitrile) / CCl₄ / 2 h / Heating

2: 95 percent / 2 h / 160 °C

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane; 2: Michalis-Arbuzov reaction;

DOI:10.1080/15421400601021505

upstream raw materials:

1-bromo-4-(bromomethyl)-2,5-bis(2-ethylhexyloxy)benzene

triethyl phosphite

3-bromomethylheptane

2-methylbenzene-1,4-diol

Downstream raw materials:

(E,E)-1,4-bis[4-bromo-2,5-bis(2-ethylhexyloxy)styryl]-2-(3,7-dimethyloctyloxy)-5-methoxybezene

C₅₂H₈₆BrNO₄Si

(E,E)-1,4-bis[4-(trimethylsilyl)ethynyl-2,5-bis(2-ethylhexyloxy)styryl]-2-(3,7-dimethyloctyloxy)-5-methoxybezene

4-{2,5-bis(2-ethylhexyloxy)-4-[(E)-2-(5-bromothiophen-2-yl)vinyl]styryl}-N,N-diethylphenylamine