Technology Process of C28H35N3O4S
There total 4 articles about C28H35N3O4S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
tert-butyl 4-(2-(2-propylpyridin-4-yl)thiazol-4-yl)phenylcarbamate;
With
sodium hydride;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 2h;
Ethyl 4-bromobutyrate;
With
sodium iodide;
In
N,N-dimethyl-formamide;
for 18h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium t-butanolate / tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis(diphenylphosphino)biphenyl / toluene / 20 h / 100 °C / Sealed tube
2.1: hydrogenchloride / tetrahydrofuran; water / 2 h / 20 °C
3.1: dmap / tetrahydrofuran / 17 h
4.1: sodium hydride / N,N-dimethyl-formamide / 2 h / 20 °C
4.2: 18 h
With
hydrogenchloride; dmap; sodium hydride; sodium t-butanolate;
tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis(diphenylphosphino)biphenyl;
In
tetrahydrofuran; water; N,N-dimethyl-formamide; toluene;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: dmap / tetrahydrofuran / 17 h
2.1: sodium hydride / N,N-dimethyl-formamide / 2 h / 20 °C
2.2: 18 h
With
dmap; sodium hydride;
In
tetrahydrofuran; N,N-dimethyl-formamide;