C₂₈H₂₂O₆

Base Information

• Chemical Name: C₂₈H₂₂O₆
• CAS No.: 1111942-24-5
• Molecular Formula: C₂₈H₂₂O₆
• Molecular Weight: 454.479
• Mol file: 1111942-24-5.mol

Synonyms:C₂₈H₂₂O₆

Chemical Property of C₂₈H₂₂O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₂₂O₆

There total 12 articles about C₂₈H₂₂O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

(E)-2-(3,5-dimethoxyphenyl)-4,6-dimethoxy-1-(4-methoxybenzylidene)-3-(4-methoxyphenyl)-2,3-dihydro-1H-indene → C28H22O6 (1111942-24-5) + (±)-quadrangularin A

Guidance literature:

With boron tribromide; In dichloromethane; at 25 ℃; for 6h;

DOI:10.1002/anie.200703333

Reference yield: 43.0%

C34H34O6 → C28H22O6 (1111942-24-5)

Guidance literature:

With boron tribromide; In dichloromethane; at 0 - 25 ℃; for 8h; Inert atmosphere;

DOI:10.1016/j.tetlet.2011.03.002

Reference yield:

1,2-bis(3,5-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one → C28H22O6 (1111942-24-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: boron trifluoride diethyl etherate / dichloromethane / 40 h / 25 °C / Inert atmosphere

2.1: sodium tetrahydroborate / tetrahydrofuran; methanol / 0.5 h / 25 °C

3.1: indium(III) triflate / dichloromethane / 1 h / 25 °C / Darkness

4.1: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.42 h / 0 - 25 °C

4.2: 12 h / 80 °C

5.1: boron tribromide / dichloromethane / 8 h / 0 - 25 °C / Inert atmosphere

With indium(III) triflate; sodium tetrahydroborate; boron trifluoride diethyl etherate; boron tribromide; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; methanol; dichloromethane; 1.1: Nazarov cyclization / 4.1: Ramberg-B?cklund olefination / 4.2: Ramberg-B?cklund olefination;

DOI:10.1016/j.tetlet.2011.03.002

upstream raw materials:

1,2-bis(3,5-dimethoxyphenyl)ethane-1,2-dione

<(4-methoxyphenyl)methyl>diphenylphosphine oxide

3,5-dimethoxybenzoic acid

p-methoxybenzyl chloride