methyl (S)-2-(2-((1H-Indol-4-yl)(methyl)amino)-3-methylbutanamido)acrylate

Base Information

Chemical Name:methyl (S)-2-(2-((1H-Indol-4-yl)(methyl)amino)-3-methylbutanamido)acrylate
CAS No.:1271141-46-8
Molecular Formula:C₁₈H₂₃N₃O₃
Molecular Weight:329.399
Hs Code.:

Synonyms:methyl (S)-2-(2-((1H-Indol-4-yl)(methyl)amino)-3-methylbutanamido)acrylate

Suppliers and Price of methyl (S)-2-(2-((1H-Indol-4-yl)(methyl)amino)-3-methylbutanamido)acrylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of methyl (S)-2-(2-((1H-Indol-4-yl)(methyl)amino)-3-methylbutanamido)acrylate

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of methyl (S)-2-(2-((1H-Indol-4-yl)(methyl)amino)-3-methylbutanamido)acrylate

There total 22 articles about methyl (S)-2-(2-((1H-Indol-4-yl)(methyl)amino)-3-methylbutanamido)acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1271142-20-1
C₂₀H₂₇N₃O₅

: 1271141-46-8
methyl (S)-2-(2-((1H-Indol-4-yl)(methyl)amino)-3-methylbutanamido)acrylate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 65 ℃; for 10h; Inert atmosphere;
DOI:10.1021/ja200437g

Reference yield: 50.0%

: methyl N-methyl-N-(1-tosyl-1H-indol-4-yl)-L-valyl-L-serinate

: 1271141-46-8
methyl (S)-2-(2-((1H-Indol-4-yl)(methyl)amino)-3-methylbutanamido)acrylate

Guidance literature:: With magnesium; In methanol; at 20 ℃; for 7h; Temperature; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.orglett.6b00614

Reference yield:

: C₁₈H₂₅N₃O₄

: 1271141-46-8
methyl (S)-2-(2-((1H-Indol-4-yl)(methyl)amino)-3-methylbutanamido)acrylate

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / 72 h / 23 °C / Inert atmosphere

2: potassium carbonate / N,N-dimethyl-formamide / 10 h / 65 °C / Inert atmosphere

With potassium carbonate; In acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/ja200437g