N-[3-fluoro-4-(1H-imidazol-1-yl)phenyl]acetamide

Base Information

Chemical Name:N-[3-fluoro-4-(1H-imidazol-1-yl)phenyl]acetamide
CAS No.:154164-57-5
Molecular Formula:C₁₁H₁₀FN₃O
Molecular Weight:219.218
Hs Code.:
DSSTox Substance ID:DTXSID001237397

Synonyms:N-[3-fluoro-4-(1H-imidazol-1-yl)phenyl]acetamide;DTXSID001237397;AKOS034537714;154164-57-5;Z729429800

Suppliers and Price of N-[3-fluoro-4-(1H-imidazol-1-yl)phenyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of N-[3-fluoro-4-(1H-imidazol-1-yl)phenyl]acetamide

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:219.08079011
Heavy Atom Count:16
Complexity:262

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)NC1=CC(=C(C=C1)N2C=CN=C2)F

Technology Process of N-[3-fluoro-4-(1H-imidazol-1-yl)phenyl]acetamide

There total 3 articles about N-[3-fluoro-4-(1H-imidazol-1-yl)phenyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 108-24-7
acetic anhydride

: 190200-19-2
3-fluoro-4-(1H-imidazol-1-yl)phenylamine

: 154164-57-5
N-(3-Fluoro-4-imidazol-1-yl-phenyl)-acetamide

Guidance literature:: With triethylamine; In chloroform; for 1.5h; Ambient temperature;

Reference yield:

: 369-34-6
3,4-difluoronitrobenzene

: 154164-57-5
N-(3-Fluoro-4-imidazol-1-yl-phenyl)-acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / dimethylformamide / 80 °C

2: 8.1 g / H₂ / Raney Ni / ethanol / 760 Torr

3: 84 percent / Et₃N / CHCl₃ / 1.5 h / Ambient temperature

With hydrogen; triethylamine; nickel; In ethanol; chloroform; N,N-dimethyl-formamide;

Reference yield:

: 154164-56-4
3-fluoro-4-(1H-imidazol-1-yl)nitrobenzene

: 154164-57-5
N-(3-Fluoro-4-imidazol-1-yl-phenyl)-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 8.1 g / H₂ / Raney Ni / ethanol / 760 Torr

2: 84 percent / Et₃N / CHCl₃ / 1.5 h / Ambient temperature

With hydrogen; triethylamine; nickel; In ethanol; chloroform;