Technology Process of 1-<3-(4-morpholinylmethyl)phenyl>cyclopentanemethanamine
There total 4 articles about 1-<3-(4-morpholinylmethyl)phenyl>cyclopentanemethanamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
ammonia; hydrogen;
nickel;
In
methanol;
for 18h;
under 2585.7 Torr;
Ambient temperature;
DOI:10.1021/jm00037a016
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 90 percent / NaH / diethyl ether; dimethylsulfoxide / 20 h / Ambient temperature
2: 86 percent / N-bromosuccinimide, benzoyl peroxide / CCl4 / 4.5 h / Heating
3: 70 percent / CH2Cl2 / 20 h
4: 96 percent / H2, NH3 / Raney nickel / methanol / 18 h / 2585.7 Torr / Ambient temperature
With
N-Bromosuccinimide; Perbenzoic acid; ammonia; hydrogen; sodium hydride;
nickel;
In
methanol; tetrachloromethane; diethyl ether; dichloromethane; dimethyl sulfoxide;
DOI:10.1021/jm00037a016
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 86 percent / N-bromosuccinimide, benzoyl peroxide / CCl4 / 4.5 h / Heating
2: 70 percent / CH2Cl2 / 20 h
3: 96 percent / H2, NH3 / Raney nickel / methanol / 18 h / 2585.7 Torr / Ambient temperature
With
N-Bromosuccinimide; Perbenzoic acid; ammonia; hydrogen;
nickel;
In
methanol; tetrachloromethane; dichloromethane;
DOI:10.1021/jm00037a016
