C₂₈H₄₅N₃O₈Si

Base Information

• Chemical Name: C₂₈H₄₅N₃O₈Si
• CAS No.: 1426656-09-8
• Molecular Formula: C₂₈H₄₅N₃O₈Si
• Molecular Weight: 579.766
• Mol file: 1426656-09-8.mol

Synonyms:C₂₈H₄₅N₃O₈Si

Chemical Property of C₂₈H₄₅N₃O₈Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₄₅N₃O₈Si

There total 10 articles about C₂₈H₄₅N₃O₈Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

C28H47N3O7Si (1426657-17-1) → C28H45N3O8Si (1426656-09-8)

Guidance literature:

With sodium periodate; rhodium(III) chloride hydrate; In water; acetone; acetonitrile; at 20 - 25 ℃; for 2h; Inert atmosphere;

DOI:10.1039/c3cc00178d

Reference yield:

C34H61N3O7Si2 (1426656-67-8) → C28H45N3O8Si (1426656-09-8)

Guidance literature:

Multi-step reaction with 2 steps

1: (1S)-10-camphorsulfonic acid / dichloromethane; methanol / 2 h / 0 - 20 °C / Inert atmosphere

2: sodium periodate; rhodium(III) chloride hydrate / acetonitrile; water; acetone / 2 h / 20 - 25 °C / Inert atmosphere

With sodium periodate; rhodium(III) chloride hydrate; (1S)-10-camphorsulfonic acid; In methanol; dichloromethane; water; acetone; acetonitrile;

DOI:10.1039/c3cc00178d

Reference yield:

(2R,3R)-(+)-2-azido-3-isopropyl-3-hydroxypropionic acid (159718-22-6) → C28H45N3O8Si (1426656-09-8)

Guidance literature:

Multi-step reaction with 6 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 0 °C / Inert atmosphere

2: silver cyanide / toluene / 1 h / 0 - 80 °C / Inert atmosphere

3: triphenylphosphine / tetrahydrofuran; water / 18 h / Inert atmosphere; Reflux

4: triethylamine / dichloromethane / 1 h / 0 °C / Inert atmosphere

5: (1S)-10-camphorsulfonic acid / dichloromethane; methanol / 2 h / 0 - 20 °C / Inert atmosphere

6: sodium periodate; rhodium(III) chloride hydrate / acetonitrile; water; acetone / 2 h / 20 - 25 °C / Inert atmosphere

With sodium periodate; silver cyanide; oxalyl dichloride; rhodium(III) chloride hydrate; (1S)-10-camphorsulfonic acid; triethylamine; N,N-dimethyl-formamide; triphenylphosphine; In tetrahydrofuran; methanol; dichloromethane; water; acetone; toluene; acetonitrile;

DOI:10.1039/c3cc00178d

upstream raw materials:

C₃₄H₆₁N₃O₇Si₂

C₂₈H₄₇N₃O₇Si

(2R,3R)-(+)-2-azido-3-isopropyl-3-hydroxypropionic acid

(2R,3R)-(+)-ethyl 2-azido-3-isopropyl-3-hydroxypropionate

Downstream raw materials:

C₃₃H₅₆N₄O₈Si

C₃₇H₆₁N₇O₉Si

actinoramide A

C₃₇H₆₀N₆O₉Si