(2R,3R)-1-methoxyspirobrassinol (1S,2R,5S)-menthyl ether

Base Information

• Chemical Name: (2R,3R)-1-methoxyspirobrassinol (1S,2R,5S)-menthyl ether
• CAS No.: 960207-08-3
• Molecular Formula: C₂₂H₃₂N₂O₂S₂
• Molecular Weight: 420.64
• Mol file: 960207-08-3.mol

Synonyms:(2R,3R)-1-methoxyspirobrassinol (1S,2R,5S)-menthyl ether

Chemical Property of (2R,3R)-1-methoxyspirobrassinol (1S,2R,5S)-menthyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of (2R,3R)-1-methoxyspirobrassinol (1S,2R,5S)-menthyl ether

There total 2 articles about (2R,3R)-1-methoxyspirobrassinol (1S,2R,5S)-menthyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

(1S)-isomenthol (20752-33-4) + 1-methoxybrassinin (105748-60-5) → (2R,3R)-1-methoxyspirobrassinol (1S,2R,5S)-menthyl ether (960207-08-3) + (2R,3S)-1-methoxyspirobrassinol (1S,2R,5S)-menthyl ether + (2S,3S)-1-methoxyspirobrassinol (1S,2R,5S)-menthyl ether + (2S,3R)-1-methoxyspirobrassinol (1S,2R,5S)-menthyl ether

Guidance literature:

With bromine; triethylamine; In dichloromethane; at 20 ℃; for 0.333333h; Solvent; Molecular sieve;

DOI:10.1016/j.tetasy.2014.07.006

Reference yield: 38.0%

(-)-neomenthol (20747-49-3) + 1-methoxybrassinin (105748-60-5) → (2R,3R)-1-methoxyspirobrassinol (1S,2R,5S)-menthyl ether (960207-08-3) + (2R,3S)-1-methoxyspirobrassinol (1S,2R,5S)-menthyl ether + (2S,3S)-1-methoxyspirobrassinol (1S,2R,5S)-menthyl ether + (2S,3R)-1-methoxyspirobrassinol (1S,2R,5S)-menthyl ether

Guidance literature:

With bromine; triethylamine; In dichloromethane; for 0.333333h;

DOI:10.1016/j.tetlet.2007.09.080

Reference yield: 62.0%

(2R,3R)-1-methoxyspirobrassinol (1S,2R,5S)-menthyl ether (960207-08-3) + m,p-dichloroaniline (95-76-1) → C18H17Cl2N3OS2 (1351000-37-7) + C18H17Cl2N3OS2

Guidance literature:

With trifluoroacetic acid; In dichloromethane; for 1.5h; Molecular sieve;

DOI:10.1016/j.tetasy.2014.07.006

upstream raw materials:

(-)-neomenthol

1-methoxybrassinin

(1S)-isomenthol

Downstream raw materials:

C₁₈H₁₇Cl₂N₃OS₂

C₁₉H₁₈F₃N₃OS₂

C₁₉H₂₁N₃OS₂