Technology Process of trans-6-(3,3,5,5-tetramethylcyclohexen-1-yl)-2,2,4,4-tetramethylcyclohexane-1-borinic acid
There total 4 articles about trans-6-(3,3,5,5-tetramethylcyclohexen-1-yl)-2,2,4,4-tetramethylcyclohexane-1-borinic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) cupric acetate / 1) ether, room temperature, 0.5 h; 2) reflux, 4 h, room temperature (overnight)
2: 42 percent / aluminum amalgam, / CH2Cl2 / 5 h / Heating
3: 89 percent / POCl3, pyridine / 18 h / Heating
4: 1.) BH3-THF, 2.) aq. H2O2, aq. NaOH / 1) 1 - 3 deg C, 16 h; 2) 46 -50 deg C, 3 h
With
pyridine; sodium hydroxide; borane-THF; aluminium amalgam; dihydrogen peroxide; copper diacetate; trichlorophosphate;
In
dichloromethane;
DOI:10.1021/ja00395a028
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 42 percent / aluminum amalgam, / CH2Cl2 / 5 h / Heating
2: 89 percent / POCl3, pyridine / 18 h / Heating
3: 1.) BH3-THF, 2.) aq. H2O2, aq. NaOH / 1) 1 - 3 deg C, 16 h; 2) 46 -50 deg C, 3 h
With
pyridine; sodium hydroxide; borane-THF; aluminium amalgam; dihydrogen peroxide; trichlorophosphate;
In
dichloromethane;
DOI:10.1021/ja00395a028
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 89 percent / POCl3, pyridine / 18 h / Heating
2: 1.) BH3-THF, 2.) aq. H2O2, aq. NaOH / 1) 1 - 3 deg C, 16 h; 2) 46 -50 deg C, 3 h
With
pyridine; sodium hydroxide; borane-THF; dihydrogen peroxide; trichlorophosphate;
DOI:10.1021/ja00395a028
