Technology Process of 2-(4-bromobutyl)-4-(4-tolyl)-5,6,7,8-tetrahydro-pyrido[1,2-c]pyrimidine-1,3-dione
There total 7 articles about 2-(4-bromobutyl)-4-(4-tolyl)-5,6,7,8-tetrahydro-pyrido[1,2-c]pyrimidine-1,3-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
acetone;
for 19h;
Heating;
- Guidance literature:
-
With
platinum on activated charcoal; hydrogen; acetic acid;
at 50 ℃;
for 10h;
under 45603.1 Torr;
DOI:10.1016/j.ejmech.2009.07.007
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium hydroxide / dimethyl sulfoxide
2: sulfuric acid; acetic acid
3: sodium ethanolate / ethanol
4: potassium carbonate / acetone
5: palladium 10% on activated carbon; hydrogen / ethanol
With
sulfuric acid; palladium 10% on activated carbon; hydrogen; sodium ethanolate; potassium carbonate; acetic acid; potassium hydroxide;
In
ethanol; dimethyl sulfoxide; acetone;
DOI:10.1016/j.ejmech.2015.05.003
