7-Oxo-6-(2-phenoxy-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2,3,3-tricarboxylic acid dimethyl ester

Base Information

Chemical Name:7-Oxo-6-(2-phenoxy-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2,3,3-tricarboxylic acid dimethyl ester
CAS No.:95477-44-4
Molecular Formula:C₁₈H₁₈N₂O₉S
Molecular Weight:438.415
Hs Code.:

Synonyms:7-Oxo-6-(2-phenoxy-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2,3,3-tricarboxylic acid dimethyl ester

Suppliers and Price of 7-Oxo-6-(2-phenoxy-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2,3,3-tricarboxylic acid dimethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7-Oxo-6-(2-phenoxy-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2,3,3-tricarboxylic acid dimethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7-Oxo-6-(2-phenoxy-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2,3,3-tricarboxylic acid dimethyl ester

There total 6 articles about 7-Oxo-6-(2-phenoxy-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2,3,3-tricarboxylic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 95477-41-1,95512-28-0
7-Oxo-6-(2-phenoxy-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2,3,3-tricarboxylic acid dimethyl ester 4-nitro-benzyl ester

: 95477-44-4
7-Oxo-6-(2-phenoxy-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2,3,3-tricarboxylic acid dimethyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In tetrahydrofuran;
DOI:10.1016/S0040-4039(01)91387-5

Reference yield:

: 66260-72-8,71698-45-8
[4-oxo-3-(2-phenoxy-acetylamino)-azetidin-2-ylsulfanyl]-malonic acid dimethyl ester

: 95477-44-4
7-Oxo-6-(2-phenoxy-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2,3,3-tricarboxylic acid dimethyl ester

Guidance literature:: Multi-step reaction with 4 steps

2: thionyl cholride

3: triethylamine

4: 28 percent / H₂ / Pd/C / tetrahydrofuran

With thionyl chloride; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran;
DOI:10.1016/S0040-4039(01)91387-5

Reference yield:

: 73395-53-6
N-[2-(Benzothiazol-2-yldisulfanyl)-4-oxo-azetidin-3-yl]-2-phenoxy-acetamide

: 95477-44-4
7-Oxo-6-(2-phenoxy-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2,3,3-tricarboxylic acid dimethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 81 percent / NaH / tetrahydrofuran / 0.75 h / 0 °C

3: thionyl cholride

4: triethylamine

5: 28 percent / H₂ / Pd/C / tetrahydrofuran

With thionyl chloride; hydrogen; sodium hydride; triethylamine; palladium on activated charcoal; In tetrahydrofuran;
DOI:10.1016/S0040-4039(01)91387-5