11-TRANS LEUKOTRIENE E4

Base Information

Chemical Name:11-TRANS LEUKOTRIENE E4
CAS No.:75715-88-7
Molecular Formula:C₂₃H₃₇NO₅S
Molecular Weight:439.616
Hs Code.:
Mol file:75715-88-7.mol

Synonyms:11-trans-LeukotrieneE4

Suppliers and Price of 11-TRANS LEUKOTRIENE E4

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
11-transLeukotrieneE4
25μg
$ 155.00

TRC
11-transLeukotrieneE4
50μg
$ 250.00

Cayman Chemical
11-trans Leukotriene E4 ≥97%
50μg
$ 184.00

Cayman Chemical
11-trans Leukotriene E4 ≥97%
25μg
$ 97.00

Cayman Chemical
11-trans Leukotriene E4 ≥97%
100μg
$ 346.00

AHH
5S-Hydroxy-6R-(S-cysteinyl)-7E,9E,11E,14Z-eicosatetraenoicacid 97%
0.00025g
$ 888.00

Total 3 raw suppliers

Chemical Property of 11-TRANS LEUKOTRIENE E4

Chemical Property:

PSA：146.15000
LogP:5.01140

Purity/Quality:

99% ^*data from raw suppliers

11-transLeukotrieneE4 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans LTE4 is equipotent to LTE4 in contracting guinea pig ileum.
Uses 11-trans Leukotriene E4 is an equipotent C-11 double bond isomer of LTE4.

Technology Process of 11-TRANS LEUKOTRIENE E4

There total 18 articles about 11-TRANS LEUKOTRIENE E4 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17814-85-6
(4-carboxybutyl)triphenylphosphonium bromide

: 75443-89-9,75715-88-7,75715-89-8,82468-17-5,84823-21-2,84823-22-3,84823-23-4,84823-24-5,84823-25-6,92009-31-9,130010-34-3,130010-35-4
(7E,9E,11Z,14Z)-(5R,6S)-6-(2-Amino-2-carboxy-ethylsulfanyl)-5-hydroxy-icosa-7,9,11,14-tetraenoic acid

Guidance literature:: Multi-step reaction with 10 steps

1: dimsyl sodium

2: PhSSPh / cyclohexane / 4 h / Irradiation

4: m-CPBA / CH₂Cl₂

5: NaIO₄, H₂O / acetic acid

6: 84 percent / benzene / Heating

7: 34 percent / benzene / Heating

8: 56 percent

9: (C₂H₅)3N / methanol

10: K₂CO₃ / methanol; H₂O

With sodium periodate; water; sodium methylsulfinylmethanide; potassium carbonate; triethylamine; 3-chloro-benzenecarboperoxoic acid; diphenyldisulfane; In methanol; dichloromethane; cyclohexane; water; acetic acid; benzene;
DOI:10.1016/S0040-4039(01)82844-6

Reference yield:

: 75415-34-8,78419-55-3,80657-04-1,80657-05-2,80657-06-3,80657-07-4,80657-08-5,80657-09-6
(7E,9E,11Z,14Z)-(5S,6R)-5-Hydroxy-6-[2-methoxycarbonyl-2-(2,2,2-trifluoro-acetylamino)-ethylsulfanyl]-icosa-7,9,11,14-tetraenoic acid methyl ester

: 75443-89-9,75715-88-7,75715-89-8,82468-17-5,84823-21-2,84823-22-3,84823-23-4,84823-24-5,84823-25-6,92009-31-9,130010-34-3,130010-35-4
(7E,9E,11Z,14Z)-(5R,6S)-6-(2-Amino-2-carboxy-ethylsulfanyl)-5-hydroxy-icosa-7,9,11,14-tetraenoic acid

Guidance literature:: With potassium carbonate; In methanol; water;
DOI:10.1016/S0040-4039(01)82844-6

Reference yield:

: 73958-09-5
Phosphorane of (Z)-3-nonen-1-yl-triphenylphosponium bromide

: 75443-89-9,75715-88-7,75715-89-8,82468-17-5,84823-21-2,84823-22-3,84823-23-4,84823-24-5,84823-25-6,92009-31-9,130010-34-3,130010-35-4
7Z,9E,11E,14Z-LTE₄

Guidance literature:: Multi-step reaction with 3 steps

1: 65 percent / tetrahydrofuran / 0.25 h / -78 °C

2: (C₂H₅)3N / methanol

3: K₂CO₃

With potassium carbonate; triethylamine; In tetrahydrofuran; methanol;
DOI:10.1002/ardp.19843170716