1-Azatricyclo[4.2.0.02,4]octane-2-carboxylicacid,8-oxo-,(2alpha,4alpha,6alpha)-(9CI)

Base Information

Chemical Name:1-Azatricyclo[4.2.0.02,4]octane-2-carboxylicacid,8-oxo-,(2alpha,4alpha,6alpha)-(9CI)
CAS No.:736100-37-1
Molecular Formula:C₈H₉NO₃
Molecular Weight:167.164
Hs Code.:
Mol file:736100-37-1.mol

Synonyms:1-Azatricyclo[4.2.0.02,4]octane-2-carboxylicacid,8-oxo-,(2alpha,4alpha,6alpha)-(9CI)

Suppliers and Price of 1-Azatricyclo[4.2.0.02,4]octane-2-carboxylicacid,8-oxo-,(2alpha,4alpha,6alpha)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 1-Azatricyclo[4.2.0.02,4]octane-2-carboxylicacid,8-oxo-,(2alpha,4alpha,6alpha)-(9CI)

Chemical Property:

Boiling Point:403.6±24.0 °C(Predicted)
PKA:3.84±0.20(Predicted)
PSA：57.61000
Density:1.59±0.1 g/cm3(Predicted)
LogP:-0.22780

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-Azatricyclo[4.2.0.02,4]octane-2-carboxylicacid,8-oxo-,(2alpha,4alpha,6alpha)-(9CI)

There total 8 articles about 1-Azatricyclo[4.2.0.02,4]octane-2-carboxylicacid,8-oxo-,(2alpha,4alpha,6alpha)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 107668-29-1,107741-65-1
p-nitrobenzyl (2RS,4SR,6RS)-8-oxo-1-azatricyclo<4.2.0.0^2,4>octane-2-carboxylate

: 736100-37-1
(2R,4S,6R)-8-Oxo-1-aza-tricyclo[4.2.0.0^2,4]octane-2-carboxylic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In 1,4-dioxane; water; for 0.25h;

Reference yield:

: 107668-29-1,107741-65-1
p-nitrobenzyl (2RS,4SR,6SR)-8-oxo-1-azatricyclo<4.2.0.0^2,4>octane-2-carboxylate

: 736100-37-1
(2R,4S,6S)-8-Oxo-1-aza-tricyclo[4.2.0.0^2,4]octane-2-carboxylic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In 1,4-dioxane; water; for 0.25h;

Reference yield:

: 68486-02-2
4-Nitrobenzyl 7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate

: 736100-37-1
(2R,4S,6R)-8-Oxo-1-aza-tricyclo[4.2.0.0^2,4]octane-2-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 20 percent / CH₂Cl₂; diethyl ether / 1 h / Ambient temperature

2: 87 percent / ethyl acetate / 1.5 h / Heating

3: H₂ / 5percent Pd-C / dioxane; H₂O / 0.25 h

With hydrogen; palladium on activated charcoal; In 1,4-dioxane; diethyl ether; dichloromethane; water; ethyl acetate;