C₂₂H₁₂Br₂

Base Information

• Chemical Name: C₂₂H₁₂Br₂
• CAS No.: 292868-56-5
• Molecular Formula: C₂₂H₁₂Br₂
• Molecular Weight: 436.145
• Mol file: 292868-56-5.mol

Synonyms:C₂₂H₁₂Br₂

Chemical Property of C₂₂H₁₂Br₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₂₂H₁₂Br₂

There total 6 articles about C₂₂H₁₂Br₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

3-bromophenylacetylene (766-81-4) + 1-(2-bromophenyl)-2-(4-iodophenyl)ethyne (292868-54-3) → C22H12Br2 (292868-56-5)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; at 20 ℃;

DOI:10.1021/jo000548o

Reference yield:

1-Bromo-3-iodobenzene (591-18-4) → C22H12Br2 (292868-56-5)

Guidance literature:

Multi-step reaction with 3 steps

1: Pd(PPh₃)2Cl₂; CuI; Et₃N / 3 h / 20 °C

2: Pd(PPh₃)2Cl₂TBAF / tetrahydrofuran / 1 h / 20 °C

3: 57 percent / Pd(PPh₃)2Cl₂; CuI; Et₃N / 20 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; tetrabutyl ammonium fluoride; triethylamine; In tetrahydrofuran; 1: Substitution / 2: Substitution / 3: Substitution;

DOI:10.1021/jo000548o

Reference yield:

1-Bromo-2-iodobenzene (583-55-1) → C22H12Br2 (292868-56-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 75 percent / Pd(PPh₃)2Cl₂; CuI; Et₃N / 3 h / 20 °C

2: 62 percent / Pd(PPh₃)2Cl₂TBAF / tetrahydrofuran / 1 h / 20 °C

3: 49 percent / Pd(PPh₃)2Cl₂; CuI; Et₃N / 3 h / 20 °C

4: 57 percent / Pd(PPh₃)2Cl₂; CuI; Et₃N / 20 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; tetrabutyl ammonium fluoride; triethylamine; In tetrahydrofuran; 1: Substitution / 2: Substitution / 3: Substitution / 4: Substitution;

DOI:10.1021/jo000548o

upstream raw materials:

3-bromophenylacetylene

1-(2-bromophenyl)-2-(4-iodophenyl)ethyne

1-Bromo-3-iodobenzene

1-Bromo-2-iodobenzene

Refernces