1-((5-(2,2-dimethoxyethoxy)methyl)-2-methoxyphenyl)-1H-pyrazole

Base Information

• Chemical Name: 1-((5-(2,2-dimethoxyethoxy)methyl)-2-methoxyphenyl)-1H-pyrazole
• CAS No.: 1246811-68-6
• Molecular Formula: C₁₅H₂₀N₂O₄
• Molecular Weight: 292.335
• Mol file: 1246811-68-6.mol

Synonyms:1-((5-(2,2-dimethoxyethoxy)methyl)-2-methoxyphenyl)-1H-pyrazole

Chemical Property of 1-((5-(2,2-dimethoxyethoxy)methyl)-2-methoxyphenyl)-1H-pyrazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 1-((5-(2,2-dimethoxyethoxy)methyl)-2-methoxyphenyl)-1H-pyrazole

There total 1 articles about 1-((5-(2,2-dimethoxyethoxy)methyl)-2-methoxyphenyl)-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

NH-pyrazole (288-13-1) + 4-((2,2-dimethoxyethoxy)methyl)-2-iodo-1-methoxybenzene (1246811-79-9) → 1-((5-(2,2-dimethoxyethoxy)methyl)-2-methoxyphenyl)-1H-pyrazole (1246811-68-6)

Guidance literature:

With copper(I) oxide; caesium carbonate; In N,N-dimethyl-formamide; at 110 ℃; for 14h; Inert atmosphere;

DOI:10.1021/ja106943q

Reference yield: 76.0%

1-((5-(2,2-dimethoxyethoxy)methyl)-2-methoxyphenyl)-1H-pyrazole (1246811-68-6) → 1-(3-(2,2-dimethoxyethoxy)methylphenyl)-1H-pyrazole (1246811-75-5)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel⁽⁰⁾; 1,1,3,3-Tetramethyldisiloxane; tricyclohexylphosphine; In toluene; at 110 ℃; for 14h; Inert atmosphere;

DOI:10.1021/ja106943q

upstream raw materials:

NH-pyrazole

4-((2,2-dimethoxyethoxy)methyl)-2-iodo-1-methoxybenzene

Downstream raw materials:

1-(3-(2,2-dimethoxyethoxy)methylphenyl)-1H-pyrazole