C₁₅H₁₇BrOSi

Base Information

• Chemical Name: C₁₅H₁₇BrOSi
• CAS No.: 1352196-85-0
• Molecular Formula: C₁₅H₁₇BrOSi
• Molecular Weight: 321.289
• Mol file: 1352196-85-0.mol

Synonyms:C₁₅H₁₇BrOSi

Chemical Property of C₁₅H₁₇BrOSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of C₁₅H₁₇BrOSi

There total 2 articles about C₁₅H₁₇BrOSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

o-bromobenzyl alcohol (18982-54-2) + phenyldimethylsilyl chloride (768-33-2) → C15H17BrOSi (1352196-85-0)

Guidance literature:

With triethylamine; In diethyl ether; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1016/j.tet.2011.09.127

Reference yield: 50.0%

Dimethylphenylsilane (766-77-8) + ortho-bromobenzaldehyde (6630-33-7) → C15H17BrOSi (1352196-85-0)

Guidance literature:

With 2,6-dimethylpyridine; C₂₆H₂₀P⁽¹⁺⁾*C₃₂H₁₂BF₂₄^(1-); In acetonitrile; at 80 ℃; for 18h;

DOI:10.1021/acscatal.1c01133

Reference yield: 97.0%

C15H17BrOSi (1352196-85-0) → [2-(hydroxymethyl)phenyl]dimethyl(phenyl)silane (853955-69-8)

Guidance literature:

C₁₅H₁₇BrOSi; With lithium; In diethyl ether; at 20 ℃; for 2h; Inert atmosphere;

With water; sodium hydrogencarbonate; In diethyl ether; Inert atmosphere; Saturated solution;

DOI:10.1016/j.tet.2011.09.127

upstream raw materials:

o-bromobenzyl alcohol

phenyldimethylsilyl chloride

Dimethylphenylsilane

ortho-bromobenzaldehyde

Downstream raw materials:

[2-(hydroxymethyl)phenyl]dimethyl(phenyl)silane

Refernces

• 1、 Hudrlik, Paul F.,Hudrlik, Anne M.,Jeilani, Yassin A.. "Intramolecular nucleophilic attack at silicon in o-silylbenzyl alcohols. Generation of allyl and benzyl anion equivalents". experimental part. p. 10089 - 10096. Retrieved 2012/02/13.