11-[4-(2-Chloroethoxy)-benzyl]-8-benzyloxy-3-methoxy-5,11-dihydro-6H-benzo[a]carbazole

Base Information

• Chemical Name: 11-[4-(2-Chloroethoxy)-benzyl]-8-benzyloxy-3-methoxy-5,11-dihydro-6H-benzo[a]carbazole
• CAS No.: 250153-38-9
• Molecular Formula: C₃₃H₃₀ClNO₃
• Molecular Weight: 524.059
• Mol file: 250153-38-9.mol

Synonyms:11-[4-(2-Chloroethoxy)-benzyl]-8-benzyloxy-3-methoxy-5,11-dihydro-6H-benzo[a]carbazole

Chemical Property of 11-[4-(2-Chloroethoxy)-benzyl]-8-benzyloxy-3-methoxy-5,11-dihydro-6H-benzo[a]carbazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 11-[4-(2-Chloroethoxy)-benzyl]-8-benzyloxy-3-methoxy-5,11-dihydro-6H-benzo[a]carbazole

There total 2 articles about 11-[4-(2-Chloroethoxy)-benzyl]-8-benzyloxy-3-methoxy-5,11-dihydro-6H-benzo[a]carbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Bromomethyl-4-(2-chloro-ethoxy)-benzene (198481-13-9) + 3-Methoxy-8-benzyloxy-5,11-dihydro-6H-benzo[a]carbazole → 11-[4-(2-Chloroethoxy)-benzyl]-8-benzyloxy-3-methoxy-5,11-dihydro-6H-benzo[a]carbazole (250153-38-9)

Guidance literature:

3-Methoxy-8-benzyloxy-5,11-dihydro-6H-benzo[a]carbazole; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.166667h;

1-Bromomethyl-4-(2-chloro-ethoxy)-benzene; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 0.416667h;

Reference yield:

1-Bromomethyl-4-(2-chloro-ethoxy)-benzene (198481-13-9) + 11H-benzo[a]carbazole (239-01-0) → 11-[4-(2-Chloroethoxy)-benzyl]-8-benzyloxy-3-methoxy-5,11-dihydro-6H-benzo[a]carbazole (250153-38-9)

Guidance literature:

With NaH; In ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

piperidine (110-89-4) + 11-[4-(2-Chloroethoxy)-benzyl]-8-benzyloxy-3-methoxy-5,11-dihydro-6H-benzo[a]carbazole (250153-38-9) → 3-Methoxy-8-benzyloxy-11-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-5,11-dihydro-6H-benzo[a]carbazole (250153-39-0)

Guidance literature:

With potassium iodide; In N,N-dimethyl-formamide; at 65 ℃; for 18h;

upstream raw materials:

1-Bromomethyl-4-(2-chloro-ethoxy)-benzene

11H-benzo[a]carbazole

Downstream raw materials:

3-Methoxy-8-benzyloxy-11-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-5,11-dihydro-6H-benzo[a]carbazole