Technology Process of 6-(4-fluorophenyl)-5-methylpyridine-2-carbonitrile 1-oxide
There total 3 articles about 6-(4-fluorophenyl)-5-methylpyridine-2-carbonitrile 1-oxide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium percarbonate; trifluoromethylsulfonic anhydride;
In
acetonitrile;
at 0 - 20 ℃;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 3-chloro-benzenecarboperoxoic acid / tetrahydrofuran / 5 h / 50 °C
2: N,N-Dimethylcarbamoyl chloride / tetrahydrofuran / 2 h / Reflux
3: sodium percarbonate; trifluoromethylsulfonic anhydride / acetonitrile / 0 - 20 °C
With
sodium percarbonate; trifluoromethylsulfonic anhydride; 3-chloro-benzenecarboperoxoic acid; N,N-Dimethylcarbamoyl chloride;
In
tetrahydrofuran; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: N,N-Dimethylcarbamoyl chloride / tetrahydrofuran / 2 h / Reflux
2: sodium percarbonate; trifluoromethylsulfonic anhydride / acetonitrile / 0 - 20 °C
With
sodium percarbonate; trifluoromethylsulfonic anhydride; N,N-Dimethylcarbamoyl chloride;
In
tetrahydrofuran; acetonitrile;
