methyl salicylidene-2-phenylethylamine

Base Information

• Chemical Name: methyl salicylidene-2-phenylethylamine
• CAS No.: 5879-65-2
• Molecular Formula: C₁₆H₁₇NO
• Molecular Weight: 239.317
• Mol file: 5879-65-2.mol

Synonyms:methyl salicylidene-2-phenylethylamine

Chemical Property of methyl salicylidene-2-phenylethylamine

Chemical Property:

Purity/Quality:

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Technology Process of methyl salicylidene-2-phenylethylamine

There total 1 articles about methyl salicylidene-2-phenylethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

o-hydroxyacetophenone (118-93-4,104809-67-8) + phenethylamine (64-04-0) → methyl salicylidene-2-phenylethylamine (5879-65-2)

Guidance literature:

In methanol; at 20 ℃; for 3h;

DOI:10.1016/j.ica.2015.11.023

Reference yield: 71.0%

iron(III) chloride + methyl salicylidene-2-phenylethylamine (5879-65-2) → bis(N-methylsalicylidene-2-phenylethylamine)iron(III) chloride

Guidance literature:

In ethanol; at 20 - 60 ℃; for 2.5h;

DOI:10.1016/j.ica.2015.11.023

Reference yield:

methyl salicylidene-2-phenylethylamine (5879-65-2) + cobalt(II) chloride (7646-79-9,14543-09-0,16413-89-1) → bis(2-[(phenylethylimino)ethyl]phenoxy)cobalt(II)

Guidance literature:

With sodium hydride; In tetrahydrofuran; soln. of Schiff base in dry THF added to soln. of NaH under Ar; stirred (10 min, room temp.); CoCl2 introduced; heated to 60°C; stirred (12 h) under Ar; filtered; evapd. (vac.); residue washed with either MeOH or THF-hexane mixt.; filtered; evapd. (vac.); elem. anal.;

DOI:10.1016/j.molcata.2009.07.009

upstream raw materials:

o-hydroxyacetophenone

phenethylamine