(S)-alpha-Methylhistamine

Base Information

Chemical Name:(S)-alpha-Methylhistamine
CAS No.:75614-93-6
Molecular Formula:C₆H₁₁N₃
Molecular Weight:125.173
Hs Code.:
DSSTox Substance ID:DTXSID10662759
Nikkaji Number:J569.464G
Pharos Ligand ID:G3YKKF1WD7LU
ChEMBL ID:CHEMBL11919
Mol file:75614-93-6.mol

Synonyms:(S)-alpha-Methylhistamine;(2S)-1-(1H-imidazol-5-yl)propan-2-amine;(S)-alpha-MeHA;CHEMBL11919;Alpha-Methylhistamine-S;Tocris-0572;Lopac-H-128;D0Q8BS;GTPL1238;SCHEMBL4008535;BDBM22905;BDBM81972;DTXSID10662759;CHEBI:125525;BDBM50472559;PDSP1_000509;PDSP2_000540;AKOS006339244;NCGC00015491-01;NCGC00024659-01;NCGC00024659-02;CAS_75614-93-6;(2S)-1-(1H-Imidazol-4-yl)-2-propanamine;(2S)-1-(3H-imidazol-4-yl)propan-2-amine;alpha-methylhistamine-dihydrobromide-(S)-(+);(S)-2-(1H-Imidazol-4-yl)-1-methyl-ethylamine;EN300-1817457;BRD-K28308851-001-01-8

Suppliers and Price of (S)-alpha-Methylhistamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-(+)-α-MethylhistamineDihydrobromide
5mg
$ 305.00

J&W Pharmlab
S-(+)-2-(1H-Imidazol-4-yl)-1-methyl-ethylamine 97%
250mg
$ 470.00

J&W Pharmlab
S-(+)-2-(1H-Imidazol-4-yl)-1-methyl-ethylamine 97%
100mg
$ 285.00

J&W Pharmlab
S-(+)-2-(1H-Imidazol-4-yl)-1-methyl-ethylamine 97%
50mg
$ 193.00

J&W Pharmlab
S-(+)-2-(1H-Imidazol-4-yl)-1-methyl-ethylamine 97%
5g
$ 5880.00

J&W Pharmlab
S-(+)-2-(1H-Imidazol-4-yl)-1-methyl-ethylamine 97%
1g
$ 1580.00

J&W Pharmlab
S-(+)-2-(1H-Imidazol-4-yl)-1-methyl-ethylamine 97%
500mg
$ 840.00

American Custom Chemicals Corporation
(S)-(+)-A-METHYLHISTAMINE DIHYDROBROMIDE 95.00%
5MG
$ 501.12

Total 8 raw suppliers

Chemical Property of (S)-alpha-Methylhistamine

Chemical Property:

Vapor Pressure:4.09E-06mmHg at 25°C
Boiling Point:375.8°C at 760 mmHg
PKA:14.50±0.10(Predicted)
Flash Point:181.1°C
PSA：54.70000
Density:1.094±0.06 g/cm3(Predicted)
LogP:2.91590
Storage Temp.:Desiccate at RT
XLogP3:-0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:125.095297364
Heavy Atom Count:9
Complexity:84.4

Purity/Quality:

97% ^*data from raw suppliers

(S)-(+)-α-MethylhistamineDihydrobromide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC1=CN=CN1)N
Isomeric SMILES:C[C@@H](CC1=CN=CN1)N
Uses (S)-(+)-alpha-Methylhistamine Dihydrobromide is an H3 receptor agonist.

Technology Process of (S)-alpha-Methylhistamine

There total 5 articles about (S)-alpha-Methylhistamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 70142-15-3
R-(+)-4-(2-Amino-3-hydroxypropyl)-imidazol

: 75614-93-6
[3H]-(R)α-methylhistamine

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / tetrahydrothiophene 1,1-dioxide

2: H₂, CH₃COONa / 10percent Pd-C / aq. acetic acid

With thionyl chloride; hydrogen; sodium acetate; palladium on activated charcoal; In sulfolane; acetic acid;
DOI:10.1002/ardp.19803130810

Reference yield:

: 75614-85-6,75614-86-7
R-(-)-4-(2-Amino-3-chlorpropyl)-imidazol-dihydrochlorid

: 75614-93-6
[3H]-(R)α-methylhistamine

Guidance literature:: With hydrogen; sodium acetate; palladium on activated charcoal; In acetic acid;
DOI:10.1002/ardp.19803130810

Reference yield:

: 6341-24-8
D-histidine monohydrochloride

: 75614-93-6
[3H]-(R)α-methylhistamine

Guidance literature:: Multi-step reaction with 4 steps

1: HCl / Heating

2: LiAlH₄ / tetrahydrofuran / Heating

3: SOCl₂ / tetrahydrothiophene 1,1-dioxide

4: H₂, CH₃COONa / 10percent Pd-C / aq. acetic acid

With hydrogenchloride; lithium aluminium tetrahydride; thionyl chloride; hydrogen; sodium acetate; palladium on activated charcoal; In tetrahydrofuran; sulfolane; acetic acid;
DOI:10.1002/ardp.19803130810