C₃₁H₅₇N₃O₅Si₂

Base Information

• Chemical Name: C₃₁H₅₇N₃O₅Si₂
• CAS No.: 1426656-59-8
• Molecular Formula: C₃₁H₅₇N₃O₅Si₂
• Molecular Weight: 607.982
• Mol file: 1426656-59-8.mol

Synonyms:C₃₁H₅₇N₃O₅Si₂

Chemical Property of C₃₁H₅₇N₃O₅Si₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₁H₅₇N₃O₅Si₂

There total 7 articles about C₃₁H₅₇N₃O₅Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C31H55N5O5Si2 (1426656-49-6) → C31H57N3O5Si2 (1426656-59-8)

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; water; for 18h; Inert atmosphere; Reflux;

DOI:10.1039/c3cc00178d

Reference yield:

(2R,3R)-(+)-2-azido-3-isopropyl-3-hydroxypropionic acid (159718-22-6) → C31H57N3O5Si2 (1426656-59-8)

Guidance literature:

Multi-step reaction with 3 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 0 °C / Inert atmosphere

2: silver cyanide / toluene / 1 h / 0 - 80 °C / Inert atmosphere

3: triphenylphosphine / tetrahydrofuran; water / 18 h / Inert atmosphere; Reflux

With silver cyanide; oxalyl dichloride; N,N-dimethyl-formamide; triphenylphosphine; In tetrahydrofuran; dichloromethane; water; toluene;

DOI:10.1039/c3cc00178d

Reference yield:

(2R,3R)-(+)-ethyl 2-azido-3-isopropyl-3-hydroxypropionate (159990-09-7) → C31H57N3O5Si2 (1426656-59-8)

Guidance literature:

Multi-step reaction with 4 steps

1: lithium hydroxide; water / methanol; tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

2: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 0 °C / Inert atmosphere

3: silver cyanide / toluene / 1 h / 0 - 80 °C / Inert atmosphere

4: triphenylphosphine / tetrahydrofuran; water / 18 h / Inert atmosphere; Reflux

With silver cyanide; oxalyl dichloride; water; N,N-dimethyl-formamide; triphenylphosphine; lithium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water; toluene;

DOI:10.1039/c3cc00178d

upstream raw materials:

(2R,3R)-(+)-2-azido-3-isopropyl-3-hydroxypropionic acid

(2R,3R)-(+)-ethyl 2-azido-3-isopropyl-3-hydroxypropionate

benzyl chloroformate

C₁₉H₃₂N₂O₃Si

Downstream raw materials:

C₃₄H₆₁N₃O₇Si₂

C₂₈H₄₇N₃O₇Si

C₂₈H₄₅N₃O₈Si

C₃₃H₅₆N₄O₈Si