(2R,3S,4R,5R,6S)-5-Amino-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5R)-5-aminomethyl-3,4-dihydroxy-tetrahydro-furan-2-yloxy)-2-hydroxy-cyclohexyloxy]-2-hydroxymethyl-tetrahydro-pyran-3,4-diol

Base Information

Chemical Name:(2R,3S,4R,5R,6S)-5-Amino-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5R)-5-aminomethyl-3,4-dihydroxy-tetrahydro-furan-2-yloxy)-2-hydroxy-cyclohexyloxy]-2-hydroxymethyl-tetrahydro-pyran-3,4-diol
CAS No.:918800-20-1
Molecular Formula:C₁₇H₃₄N₄O₁₀
Molecular Weight:454.478
Hs Code.:

(2R,3S,4R,5R,6S)-5-Amino-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5R)-5-aminomethyl-3,4-dihydroxy-tetrahydro-furan-2-yloxy)-2-hydroxy-cyclohexyloxy]-2-hydroxymethyl-tetrahydro-pyran-3,4-diol

Synonyms:(2R,3S,4R,5R,6S)-5-Amino-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5R)-5-aminomethyl-3,4-dihydroxy-tetrahydro-furan-2-yloxy)-2-hydroxy-cyclohexyloxy]-2-hydroxymethyl-tetrahydro-pyran-3,4-diol

Suppliers and Price of (2R,3S,4R,5R,6S)-5-Amino-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5R)-5-aminomethyl-3,4-dihydroxy-tetrahydro-furan-2-yloxy)-2-hydroxy-cyclohexyloxy]-2-hydroxymethyl-tetrahydro-pyran-3,4-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3S,4R,5R,6S)-5-Amino-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5R)-5-aminomethyl-3,4-dihydroxy-tetrahydro-furan-2-yloxy)-2-hydroxy-cyclohexyloxy]-2-hydroxymethyl-tetrahydro-pyran-3,4-diol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3S,4R,5R,6S)-5-Amino-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5R)-5-aminomethyl-3,4-dihydroxy-tetrahydro-furan-2-yloxy)-2-hydroxy-cyclohexyloxy]-2-hydroxymethyl-tetrahydro-pyran-3,4-diol

There total 10 articles about (2R,3S,4R,5R,6S)-5-Amino-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5R)-5-aminomethyl-3,4-dihydroxy-tetrahydro-furan-2-yloxy)-2-hydroxy-cyclohexyloxy]-2-hydroxymethyl-tetrahydro-pyran-3,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: C₃₈H₃₈N₁₂O₁₃

: 918800-20-1
(2R,3S,4R,5R,6S)-5-Amino-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5R)-5-aminomethyl-3,4-dihydroxy-tetrahydro-furan-2-yloxy)-2-hydroxy-cyclohexyloxy]-2-hydroxymethyl-tetrahydro-pyran-3,4-diol

Guidance literature:: C₃₈H₃₈N₁₂O₁₃; With sodium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 0.166667h;

With trimethylphosphane; In tetrahydrofuran; for 5h;

Reference yield:

: 534-47-4,11030-86-7
Paromamine

: 918800-20-1
(2R,3S,4R,5R,6S)-5-Amino-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5R)-5-aminomethyl-3,4-dihydroxy-tetrahydro-furan-2-yloxy)-2-hydroxy-cyclohexyloxy]-2-hydroxymethyl-tetrahydro-pyran-3,4-diol

Guidance literature:: Multi-step reaction with 9 steps

1: 90 percent / trifluoromethanesulfonyl azide; Et₃N; CuSO₄ / CH₂Cl₂; methanol; H₂O

2: 67 percent / camphor sulfonic acid / dimethylformamide / 110 °C

3: pyridine

4: trifluoroacetic acid / tetrahydrofuran; H₂O / 40 °C

5: 84 percent / camphor sulfonic acid / dimethylformamide / 50 °C

6: 76 percent / N-iodosuccinimide; trifluoromethanesulfonic acid / CH₂Cl₂

7: 52 percent / aq. TFA / tetrahydrofuran / 60 °C

8: MeNH₂ / ethanol

9: PMe₃; aq. NaOH / tetrahydrofuran / 20 °C

With pyridine; sodium hydroxide; N-iodo-succinimide; trifluorormethanesulfonic acid; triflic azide; camphor-10-sulfonic acid; copper(II) sulfate; triethylamine; methylamine; trifluoroacetic acid; trimethylphosphane; In tetrahydrofuran; methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2006.09.013