6,7-dimethoxy-4,9-dimethyl-2-phenyl-2,3-dihydro-cyclopenta[b]naphthalen-1-one

Base Information

• Chemical Name: 6,7-dimethoxy-4,9-dimethyl-2-phenyl-2,3-dihydro-cyclopenta[b]naphthalen-1-one
• CAS No.: 858368-69-1
• Molecular Formula: C₂₃H₂₂O₃
• Molecular Weight: 346.426
• Mol file: 858368-69-1.mol

Synonyms:6,7-dimethoxy-4,9-dimethyl-2-phenyl-2,3-dihydro-cyclopenta[b]naphthalen-1-one

Chemical Property of 6,7-dimethoxy-4,9-dimethyl-2-phenyl-2,3-dihydro-cyclopenta[b]naphthalen-1-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6,7-dimethoxy-4,9-dimethyl-2-phenyl-2,3-dihydro-cyclopenta[b]naphthalen-1-one

There total 2 articles about 6,7-dimethoxy-4,9-dimethyl-2-phenyl-2,3-dihydro-cyclopenta[b]naphthalen-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

6,7-dimethoxy-4,9-dimethyl-2-phenyl-cyclopenta[b]naphthalen-1-one (858368-61-3) → 6,7-dimethoxy-4,9-dimethyl-2-phenyl-2,3-dihydro-cyclopenta[b]naphthalen-1-one (858368-69-1)

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; for 0.166667h;

DOI:10.1016/j.tetlet.2005.04.128

Reference yield:

6,7-dimethoxy-1,4-dimethyl-1,4-epoxy-1,4-dihydronaphthalene → 6,7-dimethoxy-4,9-dimethyl-2-phenyl-2,3-dihydro-cyclopenta[b]naphthalen-1-one (858368-69-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 82 percent / Co₂(CO)8 / CH₂Cl₂ / 18 h / 130 °C / 22800 Torr

2: 86 percent / HCl / methanol; H₂O / 6 h / Heating

3: 85 percent / H₂ / Pd/C / tetrahydrofuran / 0.17 h

With hydrogenchloride; hydrogen; palladium on activated charcoal; dicobalt octacarbonyl; In tetrahydrofuran; methanol; dichloromethane; water; 1: Pauson-Khand reaction;

DOI:10.1016/j.tetlet.2005.04.128

Reference yield: 49.0%

6,7-dimethoxy-4,9-dimethyl-2-phenyl-2,3-dihydro-cyclopenta[b]naphthalen-1-one (858368-69-1) → 6,7-dimethoxy-4,9-dimethyl-2-phenyl-1H-cyclopenta[b]naphthalene

Guidance literature:

6,7-dimethoxy-4,9-dimethyl-2-phenyl-2,3-dihydro-cyclopenta[b]naphthalen-1-one; With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 4h;

With magnesium sulfate; In toluene; Heating;

DOI:10.1016/j.tetlet.2005.04.128

upstream raw materials:

6,7-dimethoxy-4,9-dimethyl-2-phenyl-cyclopenta[b]naphthalen-1-one