(2'R)-N-[(2S)-hydroxy-(3R)-nitro-3-phenylpropanoyl]-bornane-10',2'-sultam

Base Information

• Chemical Name: (2'R)-N-[(2S)-hydroxy-(3R)-nitro-3-phenylpropanoyl]-bornane-10',2'-sultam
• CAS No.: 685507-97-5
• Molecular Formula: C₁₉H₂₄N₂O₆S
• Molecular Weight: 408.475
• Mol file: 685507-97-5.mol

Synonyms:(2'R)-N-[(2S)-hydroxy-(3R)-nitro-3-phenylpropanoyl]-bornane-10',2'-sultam

Chemical Property of (2'R)-N-[(2S)-hydroxy-(3R)-nitro-3-phenylpropanoyl]-bornane-10',2'-sultam

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of (2'R)-N-[(2S)-hydroxy-(3R)-nitro-3-phenylpropanoyl]-bornane-10',2'-sultam

There total 2 articles about (2'R)-N-[(2S)-hydroxy-(3R)-nitro-3-phenylpropanoyl]-bornane-10',2'-sultam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-nitro-1-phenylmethane (622-42-4) + (2R)-N-glyoxylbornane-10,2-sultam (123191-45-7) → (2'R)-N-[(2R)-hydroxy-(3S)-nitro-3-phenylpropanoyl]bornane-10',2'-sultam + (2'R)-N-[(2S)-hydroxy-(3R)-nitro-3-phenylpropanoyl]-bornane-10',2'-sultam (685507-97-5) + (2'R)-N-[2-hydroxy-3-nitro-3-phenylpropanoyl]bornane-10',2'-sultam

Guidance literature:

With aluminum oxide; In tetrahydrofuran; at 20 ℃; for 0.5h;

DOI:10.1016/j.tet.2004.04.005

Reference yield:

1-nitro-1-phenylmethane (622-42-4) + (2R)-N-glyoxylbornane-10,2-sultam (123191-45-7) → (2'R)-N-[(2S)-hydroxy-(3R)-nitro-3-phenylpropanoyl]-bornane-10',2'-sultam (685507-97-5) + (2'R)-N-[(2S)-hydroxy-(3S)-nitro-3-phenylpropanoyl]-bornane-10',2'-sultam

Guidance literature:

With activated A₂O₃; at 20 ℃; for 0.5h;

DOI:10.1021/jo0358269

Reference yield: 90.0%

(2'R)-N-[(2S)-hydroxy-(3R)-nitro-3-phenylpropanoyl]-bornane-10',2'-sultam (685507-97-5) → (3R)-nitro-3-phenylpropane-(1,2S)-diol

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; at 0 ℃;

DOI:10.1016/j.tet.2004.04.005

upstream raw materials:

1-nitro-1-phenylmethane

(2R)-N-glyoxylbornane-10,2-sultam