1,2-Propanediamine, 3-phenyl-

Base Information

• Chemical Name: 1,2-Propanediamine, 3-phenyl-
• CAS No.: 75543-73-6
• Molecular Formula: C9H14 N2
• Molecular Weight: 150.224
• Mol file: 75543-73-6.mol

Synonyms:1-Benzyl-1,2-ethanediamine;3-Phenyl-1,2-propanediamine

Chemical Property of 1,2-Propanediamine, 3-phenyl-

Chemical Property:

• Boiling Point: 78 - 83 °C (0.2 - 0.3 mmHg)
• PSA: 52.04000
• LogP: 1.91570

Purity/Quality:

99%min ^*data from raw suppliers

3-Phenylpropane-1,2-diamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2-Propanediamine, 3-phenyl-

There total 15 articles about 1,2-Propanediamine, 3-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

water (7732-18-5) + (S)-2-amino-3-phenylpropionamide hydrochloride (65864-22-4) → (S)-2-amino-3-phenyl-1-propylamine (75543-73-6)

Guidance literature:

In tetrahydrofuran; chloroform;

Reference yield: 85.0%

2-benzyl-2-benzamidoethylamine (132653-51-1) → (S)-2-amino-3-phenyl-1-propylamine (75543-73-6)

Guidance literature:

With hydrogenchloride; for 20h; Heating;

Reference yield: 68.0%

2-amino-3-phenylpropanenitrile (55379-75-4) → (S)-2-amino-3-phenyl-1-propylamine (75543-73-6)

Guidance literature:

2-amino-3-phenylpropanenitrile; With diisobutylaluminium hydride; In dichloromethane; at -10 - -5 ℃; for 0.75h;

With sodium hydroxide; water; In dichloromethane; at 20 ℃; for 1h;

upstream raw materials:

α-aminophenylpropiononitrile hydrochloride

(R,S)-2-amino-3-phenylpropionamide

2-benzyl-2-benzamidoethylamine

(E)-3-phenyl-1-nitroprop-1-ene

Downstream raw materials:

1,2-diamino-N,N'-bis(2,2,2-trifluoro-1,1-diphenylethylsulfenyl)-3-phenylpropane

4⁽⁵⁾-Benzyl-2-mercaptoimidazoline

1,2-bis(N-isopropylamino)-3-phenylpropane

4-benzylimidazolidine-2-thione

Refernces

• 1、 -. "Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide". . . Retrieved 2008/06/13.
• 2、 Imagawa, Kiyomi,Hata, Eiichiro,Yamada, Tohru,Mukaiyama, Teruaki. "Convenient method for one-pot preparation of 1,2-diamines from nitroolefins". . p. 291 - 292. Retrieved 2007/10/03.