di-tert-butyl (2-chloro-4-cyano-3-fluorophenyl)propanedioate

Base Information

Chemical Name:di-tert-butyl (2-chloro-4-cyano-3-fluorophenyl)propanedioate
CAS No.:1428478-97-0
Molecular Formula:C₁₈H₂₁ClFNO₄
Molecular Weight:369.82
Hs Code.:

Synonyms:di-tert-butyl (2-chloro-4-cyano-3-fluorophenyl)propanedioate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of di-tert-butyl (2-chloro-4-cyano-3-fluorophenyl)propanedioate

Chemical Property:

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Technology Process of di-tert-butyl (2-chloro-4-cyano-3-fluorophenyl)propanedioate

There total 2 articles about di-tert-butyl (2-chloro-4-cyano-3-fluorophenyl)propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 887267-38-1
3-chloro-2,4-difluorobenzonitrile

: 24424-99-5
di-tert-butyl dicarbonate

: 1428478-97-0
di-tert-butyl (2-chloro-4-cyano-3-fluorophenyl)propanedioate

Guidance literature:: di-tert-butyl dicarbonate; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.5h;

3-chloro-2,4-difluorobenzonitrile; In N,N-dimethyl-formamide; mineral oil; at 0 - 80 ℃; for 12h;

Reference yield:

: 887267-38-1
3-chloro-2,4-difluorobenzonitrile

: 541-16-2
t-butyl malonate

: 1428478-97-0
di-tert-butyl (2-chloro-4-cyano-3-fluorophenyl)propanedioate

Guidance literature:: t-butyl malonate; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.5h;

3-chloro-2,4-difluorobenzonitrile; In N,N-dimethyl-formamide; at 0 - 80 ℃; for 12h;