2-bromoacetaldehyde methyl 2-(1-phenylpyrazol-5-yl)ethyl acetal

Base Information

Chemical Name:2-bromoacetaldehyde methyl 2-(1-phenylpyrazol-5-yl)ethyl acetal
CAS No.:1357363-00-8
Molecular Formula:C₁₄H₁₇BrN₂O₂
Molecular Weight:325.205
Hs Code.:

Synonyms:2-bromoacetaldehyde methyl 2-(1-phenylpyrazol-5-yl)ethyl acetal

Suppliers and Price of 2-bromoacetaldehyde methyl 2-(1-phenylpyrazol-5-yl)ethyl acetal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-bromoacetaldehyde methyl 2-(1-phenylpyrazol-5-yl)ethyl acetal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-bromoacetaldehyde methyl 2-(1-phenylpyrazol-5-yl)ethyl acetal

There total 2 articles about 2-bromoacetaldehyde methyl 2-(1-phenylpyrazol-5-yl)ethyl acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 7252-83-7
1-bromo-2,2-dimethoxyethane

: 1044856-44-1
2-(1-phenyl-1H-pyrazol-5-yl)ethanol

: 1357363-00-8
2-bromoacetaldehyde methyl 2-(1-phenylpyrazol-5-yl)ethyl acetal

Guidance literature:: With boron trifluoride diethyl etherate; In dichloromethane; at -50 - 0 ℃; for 7h; Inert atmosphere;
DOI:10.1055/s-0031-1289607

Reference yield:

: 1126-00-7
1-phenylpyrazole

: 1357363-00-8
2-bromoacetaldehyde methyl 2-(1-phenylpyrazol-5-yl)ethyl acetal

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran / 1.5 h / -78 °C

1.2: 3 h / -78 - 20 °C

1.3: 16 h / 100 °C

2.1: boron trifluoride diethyl etherate / dichloromethane / 7 h / -50 - 0 °C / Inert atmosphere

With n-butyllithium; boron trifluoride diethyl etherate; In tetrahydrofuran; dichloromethane; 2.1: oxa-Pictet-Spengler reaction;
DOI:10.1055/s-0031-1289607