C₁₆H₁₃NO

Base Information

• Chemical Name: C₁₆H₁₃NO
• CAS No.: 457948-80-0
• Molecular Formula: C₁₆H₁₃NO
• Molecular Weight: 235.285
• Mol file: 457948-80-0.mol

Synonyms:C₁₆H₁₃NO

Chemical Property of C₁₆H₁₃NO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₁₃NO

There total 4 articles about C₁₆H₁₃NO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

→ C16H13NO (457948-80-0)

Guidance literature:

Reference yield: 52.0%

3-phenyl-propionaldehyde (104-53-0) + 2-amino-3-hydroxybenzaldehyde (1004545-97-4) → C16H13NO (457948-80-0)

Guidance literature:

With potassium hydroxide; In ethanol; at 130 ℃; for 0.666667h; Microwave irradiation; Inert atmosphere;

DOI:10.1039/c6md00381h

Reference yield:

meta-hydroxybenzaldehyde (100-83-4) → C16H13NO (457948-80-0)

Guidance literature:

Multi-step reaction with 3 steps

1: tetra(n-butyl)ammonium hydrogensulfate; isopropyl nitrate; sulfuric acid / dichloromethane / 0.25 h / 20 °C / Inert atmosphere

2: iron; hydrogenchloride / ethanol; water / 5 h / Reflux

3: potassium hydroxide / ethanol / 0.67 h / 130 °C / Microwave irradiation; Inert atmosphere

With hydrogenchloride; isopropyl nitrate; sulfuric acid; tetra(n-butyl)ammonium hydrogensulfate; iron; potassium hydroxide; In ethanol; dichloromethane; water; 3: |Friedlaender Quinoline Synthesis;

DOI:10.1039/c6md00381h

upstream raw materials:

3-phenyl-propionaldehyde

2-amino-3-hydroxybenzaldehyde

meta-hydroxybenzaldehyde

3-hydroxy-2-nitrobenzaldehyde

Downstream raw materials:

C₁₆H₁₁Br₂NO