Technology Process of (2E,4E)-5-Benzenesulfonyl-cyclodeca-2,4-dienone
There total 11 articles about (2E,4E)-5-Benzenesulfonyl-cyclodeca-2,4-dienone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1,8-diazabicyclo[5.4.0]undec-7-ene;
In
dichloromethane;
DOI:10.1021/ja00386a045
- Guidance literature:
-
Multi-step reaction with 9 steps
1: 91 percent / NaH / tetrahydrofuran / 0 °C
2: 98 percent / Dibal-H / toluene / 0 °C
3: 94 percent / MCPBA, NaOAc / CH2Cl2 / 0 °C
4: 98 percent / (COCl)2, (C2H5)3N, Me2SO / CH2Cl2 / -78 °C
5: 80 percent / KO-t-C4H9 / tetrahydrofuran / -78 °C
6: NaH / dimethylformamide / Ambient temperature
7: polymerically bound palladium(0) / tetrahydrofuran / Heating
8: 96 percent / Me2SO, (COCl)2, (C2H5)3N / CH2Cl2
9: 86 percent / DBU / CH2Cl2
With
oxalyl dichloride; polymerically bound palladium(0); potassium tert-butylate; sodium acetate; sodium hydride; diisobutylaluminium hydride; dimethyl sulfoxide; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ja00386a045
- Guidance literature:
-
Multi-step reaction with 10 steps
1: 87 percent / PCC, NaOAc / CH2Cl2
2: 91 percent / NaH / tetrahydrofuran / 0 °C
3: 98 percent / Dibal-H / toluene / 0 °C
4: 94 percent / MCPBA, NaOAc / CH2Cl2 / 0 °C
5: 98 percent / (COCl)2, (C2H5)3N, Me2SO / CH2Cl2 / -78 °C
6: 80 percent / KO-t-C4H9 / tetrahydrofuran / -78 °C
7: NaH / dimethylformamide / Ambient temperature
8: polymerically bound palladium(0) / tetrahydrofuran / Heating
9: 96 percent / Me2SO, (COCl)2, (C2H5)3N / CH2Cl2
10: 86 percent / DBU / CH2Cl2
With
oxalyl dichloride; polymerically bound palladium(0); potassium tert-butylate; sodium acetate; sodium hydride; diisobutylaluminium hydride; dimethyl sulfoxide; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; 3-chloro-benzenecarboperoxoic acid; pyridinium chlorochromate;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ja00386a045
