C₂₃H₃₀N₂O₃

Base Information

• Chemical Name: C₂₃H₃₀N₂O₃
• CAS No.: 1055233-74-3
• Molecular Formula: C₂₃H₃₀N₂O₃
• Molecular Weight: 382.503
• Mol file: 1055233-74-3.mol

Synonyms:C₂₃H₃₀N₂O₃

Chemical Property of C₂₃H₃₀N₂O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₃₀N₂O₃

There total 8 articles about C₂₃H₃₀N₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

6-[ethyl-(3-hydroxy-4-isopropylphenyl)amino]nicotinic acid methyl ester (1055233-65-2) + prenyl bromide (870-63-3) → C23H30N2O3 (1055233-74-3)

Guidance literature:

With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 60 ℃; for 17h; Inert atmosphere;

Reference yield:

C21H28N2O3 (1055233-31-2) → C23H30N2O3 (1055233-74-3)

Guidance literature:

Multi-step reaction with 2 steps

1: aluminum (III) chloride / dichloromethane

2: potassium carbonate; potassium iodide / N,N-dimethyl-formamide

With aluminum (III) chloride; potassium carbonate; potassium iodide; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ml100184k

Reference yield:

5-nitro-2-i-propylphenol (170230-13-4) → C23H30N2O3 (1055233-74-3)

Guidance literature:

Multi-step reaction with 6 steps

1.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 1.5 h

2.1: hydrogenchloride; hydrogen / palladium on activated charcoal / methanol; water / 1.5 h / 20 °C

3.1: acetic acid / 8 h / 80 °C

3.2: 18 h / 90 °C / Reflux

4.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h

4.2: 2 h

5.1: aluminum (III) chloride / dichloromethane / 7 h / 20 °C / Inert atmosphere

6.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 17 h / 60 °C / Inert atmosphere

With hydrogenchloride; aluminum (III) chloride; hydrogen; sodium hydride; potassium carbonate; acetic acid; potassium iodide; palladium on activated charcoal; In methanol; dichloromethane; water; N,N-dimethyl-formamide;

upstream raw materials:

6-[ethyl-(3-hydroxy-4-isopropylphenyl)amino]nicotinic acid methyl ester

prenyl bromide

C₂₁H₂₈N₂O₃

5-nitro-2-i-propylphenol

Downstream raw materials:

C₂₂H₂₈N₂O₃