C₁₆H₁₈BNO₃

Base Information

• Chemical Name: C₁₆H₁₈BNO₃
• CAS No.: 1301760-57-5
• Molecular Formula: C₁₆H₁₈BNO₃
• Molecular Weight: 283.135
• Mol file: 1301760-57-5.mol

Synonyms:C₁₆H₁₈BNO₃

Chemical Property of C₁₆H₁₈BNO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₁₈BNO₃

There total 5 articles about C₁₆H₁₈BNO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-4-fluorobenzaldehyde (59142-68-6) → C16H18BNO3 (1301760-57-5)

Guidance literature:

Multi-step reaction with 4 steps

1: caesium carbonate / N,N-dimethyl-formamide / 80 °C

2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 80 °C

3: sodium tetrahydroborate / tetrahydrofuran; methanol / 0 °C

4: hydrogenchloride

With hydrogenchloride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium tetrahydroborate; potassium acetate; caesium carbonate; In tetrahydrofuran; 1,4-dioxane; methanol; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.02.024

Reference yield:

C16H16BrNO2 → C16H18BNO3 (1301760-57-5)

Guidance literature:

Multi-step reaction with 3 steps

1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 80 °C

2: sodium tetrahydroborate / tetrahydrofuran; methanol / 0 °C

3: hydrogenchloride

With hydrogenchloride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium tetrahydroborate; potassium acetate; In tetrahydrofuran; 1,4-dioxane; methanol;

DOI:10.1016/j.bmcl.2011.02.024

Reference yield:

C22H28BNO4 → C16H18BNO3 (1301760-57-5)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate / tetrahydrofuran; methanol / 0 °C

2: hydrogenchloride

With hydrogenchloride; sodium tetrahydroborate; In tetrahydrofuran; methanol;

DOI:10.1016/j.bmcl.2011.02.024

upstream raw materials:

2-bromo-4-fluorobenzaldehyde

3-[(N,N-dimethylamino)methyl]phenol